2017
DOI: 10.1177/1479164117748840
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Abstract: The interrelationship between endothelial function and arterial stiffness may be different for central and peripheral arteries due to their structural and functional differences. The study aims to assess the interrelationship between central and peripheral vascular function and haemodynamics in metabolic syndrome. Thirty-seven patients [63.0 (57.5-66.0) years, 68.4% males] of metabolic syndrome (National Cholesterol Education Program - Adult Treatment Panel-III criteria) were studied. Carotid-femoral, carotid-… Show more

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Cited by 18 publications
(12 citation statements)
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“…It is therefore perhaps not surprising that inflammatory processes such as juvenile DM may also have a different effect on the arterial stiffness of separate parts of the arterial tree. In addition, other studies have suggested that carotid‐radial PWV mainly reflects microvascular endothelial dysfunction (54,55), and therefore it could be the case that juvenile DM induces such microvascular changes rather than larger structural arterial changes.…”
Section: Discussionmentioning
confidence: 99%
“…It is therefore perhaps not surprising that inflammatory processes such as juvenile DM may also have a different effect on the arterial stiffness of separate parts of the arterial tree. In addition, other studies have suggested that carotid‐radial PWV mainly reflects microvascular endothelial dysfunction (54,55), and therefore it could be the case that juvenile DM induces such microvascular changes rather than larger structural arterial changes.…”
Section: Discussionmentioning
confidence: 99%
“…49 Stiffness in the peripheral muscular arteries is of potential clinical importance. 49 Peripheral arterial stiffness may be specifically associated with peripheral vascular disease, which is linked to hypertension and diabetes, both of which are risk factors for CVD. 49,50 We further observed that oxidative stress as measured by plasma nitrotyrosine level was associated with increased arterial stiffness after adjusting for blood pressure, age and body fat mass, in line with the conceptual model in Figure 2.…”
Section: Discussionmentioning
confidence: 99%
“…Stiffening of these arteries predominantly results in functional variation, such as increased diastolic blood pressure because of increased muscle tone. 49 Stiffness in the peripheral muscular arteries is of potential clinical importance. 49 Peripheral arterial stiffness may be specifically associated with peripheral vascular disease, which is linked to hypertension and diabetes, both of which are risk factors for CVD.…”
Section: Discussionmentioning
confidence: 99%
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“…Then, the PCA-based approach ( 35 , 36 ) was used for dimension reduction of hemodynamics or vascular parameters. The first principal component (PC1) is considered the best representation of variables and utilized to construct SHI and VDI.…”
Section: Methodsmentioning
confidence: 99%