Regional aortic distensibility and its relationship with age and aortic stenosis: a computed tomography study

Wong, D.; Narayan, Om; Leong, Darryl P.; Bertaso, A.; Maia, Murilo; Ko, Brian; Baillie, T.; Seneviratne, Sujith; Worthley, M.; Meredith, Ian T.; Cameron, James D.

doi:10.1007/s10554-015-0640-z

Cited by 8 publications

(1 citation statement)

References 26 publications

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“…It is important to note that since different indices and methods of quantifying stiffness provide information from a different pathophysiological aspect, it is uncertain whether the conclusions reached by this body of studies can be interpreted comprehensively. However, with scarce exceptions [41], most of the investigators support a decrease of both proximal AD and SAC in AVS patients [16,34,[42][43][44] (Tables 1, 2 and 3).…”

Section: Other Indices Of Arterial Stiffnessmentioning

confidence: 94%

Arterial biomarkers in the evaluation, management and prognosis of aortic stenosis

et al. 2021

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Degenerative aortic valve stenosis is the most common primary valve disease and a significant cause of cardiovascular morbidity and mortality. In an era when new techniques for the management of aortic stenosis are gaining ground, the understanding of this disease is more important than ever to optimize treatment. So far, the focus has been placed on the assessment of the valve itself. However, the role that the arterial system plays in the pathogenesis and natural history of the disease needs to be further elucidated. Arteriosclerosis, when it coexists with a stenotic valve, augments the load posed on the left ventricle contributing to greater impairment of cardiovascular function. Arterial stiffness, a well-established predictor for cardiovascular disease and all-cause mortality, could play a role in the prognosis and quality of life of this population. Several studies using a variety of indices to assess arterial stiffness have tried to address the potential utility of arterial function assessment in the case of aortic stenosis. Importantly, reliable data identify a prognostic role of arterial biomarkers in aortic stenosis and stress their possible use to optimize timing and method of treatment. This review aims at summarizing the existing knowledge on the interplay between the heart and the vessels in the presence of degenerative aortic stenosis, prior, upon and after interventional management. Further, it discusses the evidence supporting the potential clinical application of arterial biomarkers for the assessment of progression, severity, management and prognosis of aortic stenosis.

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Section: Other Indices Of Arterial Stiffnessmentioning

confidence: 94%

Arterial biomarkers in the evaluation, management and prognosis of aortic stenosis

et al. 2021

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Ascending aortic distensibility and target organ damage in primary hypertension without diabetes

Chen

Wang

Sun

et al. 2017

Int J Cardiovasc Imaging

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To investigate the relationship between ascending aortic distensibility (AAD) and hypertensive target organ damage (TOD) and its potential value in prediction. One hundred and sixty seven primary hypertension inpatients who underwent coronary CTA examination were enrolled into our study. Retrospective ECG-triggering scanning mode were applied and the images were reconstructed every 5% phase in the entire R-R interval. Maximum and minimum ascending aortic areas as well as the AAD value were calculated on the interested slice. AAD (P < 0.001) and brachial-ankle pulse wave velocity (baPWV, P < 0.05) were changed significantly as the deterioration of TOD. Multivariate logistic regression analysis between TOD and its possible influence factors indicated that AAD was the only independent risk factor for the presence and severity of TOD. One standard deviation decrease on AAD would increase the risk of TOD significantly: TOD1 (odds ratio 0.45, P < 0.05), TOD2 (odds ratio 0.23, P < 0.05), and TOD3 (odds ratio 0.01, P < 0.05). The odds ratio of TOD in the third tertile group was found 5.47 times higher than that in the second tertile group, and the second tertile group TOD odds ratio was 6.4 times higher than that in the first tertile group. Decline of AAD can be taken as the independent predict factor for TOD in primary hypertension patients, superior to baPWV method and other conventional predictors. Without additional contrast media consumption and radiation dose, AAD derived from coronary CTA may provide early detection for hypertensive TOD.

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Dynamic aortic changes during the cardiac cycle in patients with aortic valve disease analyzed by computed tomography combined with PhyZiodynamics software

Norimatsu

Iguchi

Isobe

2023

Int J Cardiovasc Imaging

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Regional aortic distensibility and its relationship with age and aortic stenosis: a computed tomography study

Cited by 8 publications

References 26 publications

Arterial biomarkers in the evaluation, management and prognosis of aortic stenosis

Arterial biomarkers in the evaluation, management and prognosis of aortic stenosis

Ascending aortic distensibility and target organ damage in primary hypertension without diabetes

Dynamic aortic changes during the cardiac cycle in patients with aortic valve disease analyzed by computed tomography combined with PhyZiodynamics software

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