Regenerative Techniques for Neuraxial Back Pain: a Systematic Review

Valimahomed, Ali; Haffey, Paul Ryan; Urman, Richard D.; Kaye, Alan D.; Yong, R. Jason

doi:10.1007/s11916-019-0758-0

Cited by 8 publications

(2 citation statements)

References 21 publications

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“…A 2019 systematic review of regenerative studies identified 9 studies reporting on clinical outcomes from autologous biologic treatments for low back pain. 88 However, these were heterogenous in terms of both patient group and intervention, and only one randomised controlled trial (n = 58) was found. The trial authors reported small benefits of intradiscal platelet-rich plasma over 8 weeks with no long-term follow-up.…”

Section: Many Patients With Low Back Pain Are Still Receiving the mentioning

confidence: 99%

The Lancet Series call to action to reduce low value care for low back pain: an update

Buchbinder

Underwood

Hartvigsen

et al. 2020

Pain

155

120

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Review and comments The World Drug Report 2019 benefited from the expertise of and invaluable contributions from INCB and from UNODC colleagues in all divisions. The Research and Trend Analysis Branch acknowledges the important contribution from its colleagues in the Laboratory and Scientific Section and in the Programme Development and Management Unit. The Research and Trend Analysis Branch acknowledges the invaluable contributions and advice provided by the World Drug Report Scientific Advisory Committee:

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Section: Many Patients With Low Back Pain Are Still Receiving the mentioning

confidence: 99%

The Lancet Series call to action to reduce low value care for low back pain: an update

Buchbinder

Underwood

Hartvigsen

et al. 2020

Pain

155

120

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“…Pettine et al reported significant reductions in pain following BMAC use for patients with discogenic pain [47]. The principle caveat of these results is the scarcity of similar results demonstrated in the literature [48].…”

Section: Spondylosismentioning

confidence: 98%

Regenerative Medicine

Haroutunian¹,

Malcolm²,

Zouki³

2021

Pain Management - Practices, Novel Therapies and Bioactives

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Chronic pain is a debilitating condition that affects millions of people world-wide, leading to physical incapacitation and financial strain. Common methods for treatment include physical therapy, oral medications, injections, surgery, and neuromodulation. Injectates with steroids and local anesthetics can be a temporizing measure with intolerable side effects. The use of autologous biologic injectates (e.g., platelet rich plasma, bone marrow aspirate concentrate, tissue grafts, and stem cells) is growing in therapeutic potential and enthusiasm, giving hope to a subset of patients that have either failed conventional therapy or are not candidates for traditional steroid injections. In this chapter, we will describe different cases in which regenerative medicine can help in painful conditions as well as neuro-degenerative conditions. Regenerative medicine can be the new frontier in providing long lasting relief through changes in cell-signaling cascades, however further trials are needed to validate their use.

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Back Pain: Facet Syndrome

Rana

2022

Clinical Guide to Musculoskeletal Medicine

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Regenerative Techniques for Neuraxial Back Pain: a Systematic Review

Cited by 8 publications

References 21 publications

The Lancet Series call to action to reduce low value care for low back pain: an update

The Lancet Series call to action to reduce low value care for low back pain: an update

Regenerative Medicine

Back Pain: Facet Syndrome

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