Refractive Results of Hyperopic Hydrogel Intracorneal Lenses in Primate Eyes

Long-term follow-up of hydrogel intracorneal lenses in 2 aphakic eyes

“…New materials such as hydrogel showed biocompatibility and good corneal tolerance when implanted in primates. 2 Hydrogel lenses are permeable to water and nutrients, so normal corneal physiology can be maintained. Because of its refractive index (1.376), the lens has no refractive power on its own within the cornea.…”

Long-term follow-up of hydrogel intracorneal lenses in 2 aphakic eyes

“…New materials such as hydrogel showed biocompatibility and good corneal tolerance when implanted in primates. 2 Hydrogel lenses are permeable to water and nutrients, so normal corneal physiology can be maintained. Because of its refractive index (1.376), the lens has no refractive power on its own within the cornea.…”

Clear Lens Replacement Surgery

“…However, corneal refractive surgical treatments for high refractive errors have been plagued by refractive instability, surgical inaccuracy, healing responses that vary, small treatment zones, and limited treatment ranges. As a result, many refractive surgical procedures; such as keratophakia, epikeratophakia, 20,21 hyperopic keratomiliusis, myopic keratomiliusis, 22,23 automated keratoplasty, 24,25 hexagonal keratotomy, 26 radial keratotomy, [27][28][29] and intracorneal inlays, 30,31 have largely been abandoned. Intracorneal rings and laser thermokeratoplasty (for hyperopia) have been effective only at treating low refractive errors.…”

Refractive Predictability of Myopic Hydrogel Intracorneal Lenses in Nonhuman Primate Eyes

“…For eyes with implants at a 36% to 60% depth, the predicted vs achieved refractive alteration yielded a correlation coefficient of .97 (88% within \m=+-\3 diopters of the correlation). The refractive outcome remained stable throughout 7 months of follow-up, whereas deeply placed lenses (\m=ge\80%) exhibited significant regression in power during this time.…”

Long-term follow-up of hydrogel intracorneal lenses in 2 aphakic eyes

“…New materials such as hydrogel showed biocompatibility and good corneal tolerance when implanted in primates. 2 Hydrogel lenses are permeable to water and nutrients, so normal corneal physiology can be maintained. Because of its refractive index (1.376), the lens has no refractive power on its own within the cornea.…”

Clear Lens Replacement Surgery

“…However, corneal refractive surgical treatments for high refractive errors have been plagued by refractive instability, surgical inaccuracy, healing responses that vary, small treatment zones, and limited treatment ranges. As a result, many refractive surgical procedures; such as keratophakia, epikeratophakia, 20,21 hyperopic keratomiliusis, myopic keratomiliusis, 22,23 automated keratoplasty, 24,25 hexagonal keratotomy, 26 radial keratotomy, [27][28][29] and intracorneal inlays, 30,31 have largely been abandoned. Intracorneal rings and laser thermokeratoplasty (for hyperopia) have been effective only at treating low refractive errors.…”

Refractive Predictability of Myopic Hydrogel Intracorneal Lenses in Nonhuman Primate Eyes

“…For eyes with implants at a 36% to 60% depth, the predicted vs achieved refractive alteration yielded a correlation coefficient of .97 (88% within \m=+-\3 diopters of the correlation). The refractive outcome remained stable throughout 7 months of follow-up, whereas deeply placed lenses (\m=ge\80%) exhibited significant regression in power during this time.…”

Long-term follow-up of hydrogel intracorneal lenses in 2 aphakic eyes

“…New materials such as hydrogel showed biocompatibility and good corneal tolerance when implanted in primates. 2 Hydrogel lenses are permeable to water and nutrients, so normal corneal physiology can be maintained. Because of its refractive index (1.376), the lens has no refractive power on its own within the cornea.…”

Clear Lens Replacement Surgery

“…However, corneal refractive surgical treatments for high refractive errors have been plagued by refractive instability, surgical inaccuracy, healing responses that vary, small treatment zones, and limited treatment ranges. As a result, many refractive surgical procedures; such as keratophakia, epikeratophakia, 20,21 hyperopic keratomiliusis, myopic keratomiliusis, 22,23 automated keratoplasty, 24,25 hexagonal keratotomy, 26 radial keratotomy, [27][28][29] and intracorneal inlays, 30,31 have largely been abandoned. Intracorneal rings and laser thermokeratoplasty (for hyperopia) have been effective only at treating low refractive errors.…”

Refractive Predictability of Myopic Hydrogel Intracorneal Lenses in Nonhuman Primate Eyes

“…For eyes with implants at a 36% to 60% depth, the predicted vs achieved refractive alteration yielded a correlation coefficient of .97 (88% within \m=+-\3 diopters of the correlation). The refractive outcome remained stable throughout 7 months of follow-up, whereas deeply placed lenses (\m=ge\80%) exhibited significant regression in power during this time.…”