volume 84, issue 1, P92-117 2015
DOI: 10.1002/prot.24958
View full text
Sign up to set email alerts

Abstract: Obtaining a quantitative description of the membrane proteins stability is crucial for understanding many biological processes. However the advance in this direction has remained a major challenge for both experimental studies and molecular modeling. One of the possible directions is the use of coarse-grained models but such models must be carefully calibrated and validated. Here we use a recent progress in benchmark studies on the energetics of amino acid residue and peptide membrane insertion and membrane p…

Expand abstract