2003
DOI: 10.1253/circj.67.799
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Abstract: emolytic anemia is uncommon after mitral valve repair and only a few cases have been reported. Although it is thought that rapid acceleration, fragmentation and collision of mitral regurgitation jets may be associated with high shear stress and cause hemolysis, 1,2 the precise mechanisms are not understood. In addition, the course of severe hemolysis after mitral valve repair has not been established, although in most cases the hemolysis improves with reoperation. [2][3][4][5][6][7][8][9][10][11] We report a p… Show more

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Cited by 14 publications
(10 citation statements)
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“…[18][19][20][21] Hemolysis also complicates a small percentage (<1%) of mitral valve repair and annular ring placement surgeries. [22][23][24][25] Although ring dehiscence appears to be the main mechanism of CPAH in this group, other reported mechanisms include: protruding of the paravalvular suture material, "whiplash motion" of residual free-floating chordae in hyperkinetic ventricles, and small but turbulent eccentric residual regurgitation jet (Table 1). In this large series, valve replacement led to the resolution of hemolysis in the vast majority of cases.…”
Section: Hemolysis After Open Valve Surgerymentioning
confidence: 99%
“…[18][19][20][21] Hemolysis also complicates a small percentage (<1%) of mitral valve repair and annular ring placement surgeries. [22][23][24][25] Although ring dehiscence appears to be the main mechanism of CPAH in this group, other reported mechanisms include: protruding of the paravalvular suture material, "whiplash motion" of residual free-floating chordae in hyperkinetic ventricles, and small but turbulent eccentric residual regurgitation jet (Table 1). In this large series, valve replacement led to the resolution of hemolysis in the vast majority of cases.…”
Section: Hemolysis After Open Valve Surgerymentioning
confidence: 99%
“…Of these, the reports we chose fulfilled the following three conditions: a clear degree of MR jet as seen on Doppler echocardiography; a clear interval from initial operation to the appearance of hemolysis, and a clear oneto-one relation between the MR grade and the interval in the case series; and an absence of causes other than MR jet collision, including partial annuloplasty dehiscence, protruding paravalvular suture material, the whiplash motion of tendinous chords, or regurgitant jet collision with the pledget or atrial wall. We evaluated nine case reports and two case series of hemolysis caused by unendothelialization of the annuloplasty ring with or without MR jet collision as measured by echocardiography or reoperation (Table 3) [4,[12][13][14][15][16][17][18][19][20][21]. The cases of reoperation include seven reports and two series.…”
Section: Discussionmentioning
confidence: 99%
“…High-velocity jets increase shear forces that disrupt erythrocyte membranes and result in hemolysis [5]. Also rapid acceleration, fragmentation and collision of mitral regurgitation jets cause hemolysis [6]. In our case, echocardiography revealed severe mitral stenosis and moderate mitral regurgitation.…”
Section: Discussionmentioning
confidence: 56%