“…Examples include enhanced education services for primarily low-income, very young children to improve their cognitive, language, and socialcognitive skills; [48][49][50] and interventions that strengthen parenting skills, parent-child communication, and affective relationships. These include universal (eg, the Strengthening Families Program for Parents and Youth 10-14 28,72,73 and the Computer-Based Intervention 54,55 ), selective (eg, the New Beginnings Program 56 ), and indicated programmes (eg, Functional Family Therapy 74 ). Across programmes, significant effects were identified in early childhood to late adolescence and include reduced child abuse and neglect, alcohol and other drug misuse, risky sexual activity, depression, and delinquency and crime, and greater educational attainment.…”