2018
DOI: 10.1210/jc.2018-01674
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Abstract: Context The prevalence of thyroid nodules in the general population is increasingly high, and at least half of those biopsied prove to be benign. Sonographic risk-stratification systems are being proposed as “rule-out” tests that can identify nodules that do not require fine-needle aspiration (FNA) cytology. Objective To comparatively assess the performances of five internationally endorsed sonographic classification systems … Show more

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Cited by 228 publications
(208 citation statements)
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References 33 publications
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“…In our study, thyroid nodules with relatively TI‐RADS high scores received FNA, so total ROM of Bethesda system III/IV was 54.2%, which was significantly higher than those from Western practice, demonstrating that TI‐RADS reduces the number of unnecessary thyroid nodule FNAs . Second, as we know differentiated thyroid carcinoma (DTC) accounts for more than 90% of all thyroid cancers and DTC is an indolent carcinoma, our practice of triaging patients with Bethesda system III/IV nodules is as follows: ≥TI‐RADS 4c with Bethesda system III/IV nodules were referred to surgery; ≤TI‐RADS 4a with Bethesda system III/IV nodules were referred for routine observation, with the exception of benign thyroid nodules, which were referred to surgery; for TI‐RADS 4b with Bethesda system III/IV nodules needing further discussion with the patients, possible advice included repeat FNA diagnostic surgery, routine observation, use of other imaging modalities, and so on based on patient preference …”
Section: Resultsmentioning
confidence: 75%
See 1 more Smart Citation
“…In our study, thyroid nodules with relatively TI‐RADS high scores received FNA, so total ROM of Bethesda system III/IV was 54.2%, which was significantly higher than those from Western practice, demonstrating that TI‐RADS reduces the number of unnecessary thyroid nodule FNAs . Second, as we know differentiated thyroid carcinoma (DTC) accounts for more than 90% of all thyroid cancers and DTC is an indolent carcinoma, our practice of triaging patients with Bethesda system III/IV nodules is as follows: ≥TI‐RADS 4c with Bethesda system III/IV nodules were referred to surgery; ≤TI‐RADS 4a with Bethesda system III/IV nodules were referred for routine observation, with the exception of benign thyroid nodules, which were referred to surgery; for TI‐RADS 4b with Bethesda system III/IV nodules needing further discussion with the patients, possible advice included repeat FNA diagnostic surgery, routine observation, use of other imaging modalities, and so on based on patient preference …”
Section: Resultsmentioning
confidence: 75%
“…In our study, thyroid nodules with relatively TI-RADS high scores received FNA, so total ROM of Bethesda system III/IV was 54.2%, which was significantly higher than those from Western practice, 29,[32][33][34] demonstrating that TI-RADS reduces the number of unnecessary thyroid nodule FNAs. 35 Second, as we know differentiated thyroid carcinoma (DTC) accounts for more than 90% of all thyroid cancers and DTC is an indolent carcinoma, our practice of triaging patients with Bethesda system III/IV nodules is as follows:…”
Section: Discussionmentioning
confidence: 99%
“…The difference in the latter figure is probably due to the cytological recruitment of this study. In their report, Grani et al 22 found that application of the EU-TIRADS' FNA criteria would have reduced the number of biopsies performed by 30.7% with a false negative rate of 3.2%.…”
Section: Diagnostic Performance Of the Us Scorementioning
confidence: 99%
“…T he prediction of malignancy in thyroid nodules continues to evolve. Sonographic characteristics of thyroid nodules alone are not sufficient to predict the risk of malig-nancy for many nodules (1,2). Thyroid nodule fine-needle aspiration (FNA) is routinely performed to cytologically evaluate thyroid nodules that meet certain sonographic criteria (3,4).…”
Section: Introductionmentioning
confidence: 99%