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Cited by 29 publications
(25 citation statements)
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References 42 publications
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“…It may be that, early in diabetes, hyperfiltration is associated with elevated thrombomodulin, which remains elevated as renal disease progresses. Hyperfiltration is associated with lower tHcy (14,16), whereas elevated tHcy occurs with progressive renal impairment. Together, these results and those of Hofmann et al (10) would be consistent with this explanation: the differences in tHcy reflect different stages during the progression of nephropathy, whereas elevated thrombomodulin occurs at the early stage of hyperfiltration and then remains elevated.…”
Section: Discussionmentioning
confidence: 99%
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“…It may be that, early in diabetes, hyperfiltration is associated with elevated thrombomodulin, which remains elevated as renal disease progresses. Hyperfiltration is associated with lower tHcy (14,16), whereas elevated tHcy occurs with progressive renal impairment. Together, these results and those of Hofmann et al (10) would be consistent with this explanation: the differences in tHcy reflect different stages during the progression of nephropathy, whereas elevated thrombomodulin occurs at the early stage of hyperfiltration and then remains elevated.…”
Section: Discussionmentioning
confidence: 99%
“…Plasma thrombomodulin was measured using a commercially available sandwich enzyme-linked immunosorbent assay (Diagnostica Stago). tHcy, serum and red cell folate, and vitamin B12 were measured on the Abbott IMX analyzer, as previously reported (16). HbA 1c was measured using highperformance liquid chromatography.…”
Section: Diabetes Vol 51 July 2002mentioning
confidence: 99%
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“…A link between plasma hyperHcy and micro and macro-vascular lesions in adult patients with T1DM (4,5) and in adolescent with type 1 diabetes has been recently reported (6). The link with adolescent type 1 diabetes mellitus (T1DM) is not universally accepted, since difference in dietary intake of folates and Vit B12 (reflected by higher plasma levels) might be a confounding factor (7). It remains to be clarified if hyper-Hcy might be considered a predictor of future micro-macrovascular complications in T1DM or it simply rises, when chronic microvascular or macrovascular complications are already established.…”
Section: Introductionmentioning
confidence: 99%
“…Blood folate markers include plasma folate, a measure of recent intake, and RBC folate, which reflects long-term folate stores in the RBC. Correlations between FFQ and plasma folate levels in women range from 0?186 to 0?63 (12,(31)(32)(33)(34)(35)(36)(37)(38) , and from 0?00 to 0?28 between FFQ and RBC folate values (34,35) . These FFQ request information on the consumption of eighty-four (32) to 145 (37) food items for up to 1 year of recall (12,31,32) .…”
mentioning
confidence: 99%