Loren Mowszowski, Daniel F. Hermens, Keri Diamond, Louisa Norrie, Ian B. Hickie, Simon J.G. Lewis, Sharon L. Naismith
Abstract:Mild cognitive impairment (MCI) refers to a transitory state between healthy aging and dementia. Biomarkers are needed to facilitate early identification of MCI and predict progression to dementia. One potential neurophysiological biomarker, mismatch negativity (MMN), is an event-related potential reflecting fundamental, pre-attentive cognitive processes. MMN is reduced in normal aging and dementia and in neuropsychiatric samples and is associated with verbal memory deficits and poor executive functioning. Thi…
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