The CP T invariance has been firmly established via experimental tests. Its theoretical implication and derivation at two levels of both relativistic quantum mechanics (RQM ) and quantum field theory (QF T ) are discussed. Being a basic symmetry, the CP T invariance can be expressed as PT = C, where PT represent the "strong reflection", i.e., the (newly defined) space-time inversion (x → −x, t → −t), invented by Lüders and Pauli in the proof of the CP T theorem and C the new particleantiparticle transformation proposed by Lee and Wu. Actually, the renamed CP T invariance, PT = C, could be viewed as a basic postulate being injected implicitly into the theory since the nonrelativistic quantum mechanics (N RQM ) was combined with the theory of special relativity (SR) to become RQM and then the QF T . The Klein-Gordon (KG) equation is highlighted to become a self-consistent theory in RQM , based on two sets of wavefunctions (W F s) and momentum-energy operators for particle and antiparticle respectively, together with the above postulate. Hence the Klein paradox for both KG equation and Dirac equation can be solved without resorting to the "hole theory".