Reduced acute phase response after laparoscopic total extraperitoneal bilateral hernia repair compared to open repair with the Stoppa procedure

Abstract

The acute phase inflammatory response in clearly more active after the open Stoppa procedure than after TEPP, indicating that the former is associated with increased tissue trauma. This may play a role in the earlier recovery seen after the TEPP procedure.

Cytokine response in the postoperative period after surgical treatment of benign adnexal masses: comparison between laparoscopy and laparotomy

“…Our findings are in agreement with the literature, which shows that procedures of similar invasiveness, e.g., hernia repair or urologic surgery, are capable of inducing enough stress to reveal a difference between laparoscopy and laparotomy [43,57].…”

“…Many studies comparing laparoscopic and open approaches in the management of cholelithiasis [1,8,21,24,33,54], inguinal hernia [57], urological diseases [20,29,43], and morbid obesity [45,63] showed that minimally invasive techniques were connected with less release of inflammatory cytokines intraoperatively and postoperatively. Similar studies of more complicated procedures like colon resections or hysterectomies differ in results.…”

Accuracy of diagnostic laparoscopy for early diagnosis of abdominal complications after cardiac surgery

“…The results from our study suggest that laparotomy, with its concomitant increased surgical trauma, can safely be avoided in these cases. This could mean less stress response with fewer immunogenous alterations [1,16], thereby also helping to improve outcome in this setting. In our study, nine of 17 patients (54%) could have been diagnosed and adequately treated without laparotomy.…”

“…As we have shown, the diagnostic values of laparoscopy and laparotomy are equivalent. Laparoscopy is associated with less operative trauma and a lower systemic stress response than laparotomy [1,16], which is especially important in critically ill patients. Therefore, the indications for diagnostic laparoscopy should be expanded and abdominal inspection performed earlier, so as to enable earlier intervention and improve the outcome in these patients.…”

Surgical approach in primary total hip arthroplasty: anatomy, technique and clinical outcomes

“…This methodology has been used previously to justify the use of tissue-sparing techniques, such as laparoscopy in other surgical subspecialties. 69,70 The investigators measured pre-and postoperative values of various acute phase reactant proteins, such as creatine kinase (CK), C-reactive protein (CRP), interleukin (IL)-6, tumour necrosis factor (TNF)-α and IL-1 in 57 patients undergoing THA. They found a significant increase in CK in the posterior approach group compared with the anterior approach group immediately following the procedure as well as cumulatively 2 days after THA.…”