Redox Switchable Ionophores for Heavy and Transition Metal Cations

Cu(II)- and Hg(II)-Induced Modulation of the Fluorescence Behavior of a Redox-Active Sensor Molecule

“…In this system a simple 1,2,4-thiadiazole was attached via a methylene spacer to an anthracene fluorophore in a way that allowed photoinduced electron transfer (PET) from the receptor to the fluorophore unit to occur. It is known from the literature that selective binding of heavy metal and transition metal cations is achieved by receptors containing sulfur or nitrogen heteroatoms. , Previously, we have shown the complexation behavior of redox-switchable 1,2,4-thiadiazole/iminoyl thiourea ionophores …”

“…8,9 Previously, we have shown the complexation behavior of redox-switchable 1,2,4-thiadiazole/ iminoyl thiourea ionophores. 10 Following this modular approach, a structurally more simple 1,2,4-thiadiazole/iminoyl thiourea redox system with a naphthyl fluorophore was synthesized (Figure 1). Both forms, the heterocyclic thiadiazole 1 (oxidized form) and the ring-opened iminoyl thiourea 2 (reduced form), can be converted into each other by chemical oxidation or reduction, respectively.…”