PURPOSE OF REVIEW
Scavenger receptor BI (SR-BI) is classically known for its role in anti-atherogenic reverse cholesterol transport as it selectively takes up cholesterol esters from high-density lipoprotein (HDL). Here we have highlighted recent literature that describes novel functions for SR-BI in physiology and disease.
A large population based study has revealed that subjects heterozygous for the P376L mutant form of SR-BI showed significantly increased levels of plasma HDL-cholesterol…
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