Recurrent symmetrical drug‐related intertriginous and flexural exanthema caused by different iodinated contrast media

Contrast media and cutaneous reactions. Part 2: Delayed hypersensitivity reactions to iodinated contrast media

“…) reported to be caused by ICM (Table ). The age ranged from 57 to 80 years old; one man and three women . Three of the cases followed coronary angioplasty and/or an angiogram and one followed a CT scan .…”

“…The age ranged from 57 to 80 years old; one man 35 and three women. [36][37][38] Three of the cases followed coronary angioplasty and/or an angiogram [35][36][37] and one followed a CT scan. 38 Iomeprol was used in two cases 35,37 but the CM was unknown in the other cases.…”

“…[36][37][38] Three of the cases followed coronary angioplasty and/or an angiogram [35][36][37] and one followed a CT scan. 38 Iomeprol was used in two cases 35,37 but the CM was unknown in the other cases. 36,38 Iopromide in addition to iomeprol was also found to cause SDRIFE in one patient on two separate occasions.…”

“…38 Iomeprol was used in two cases 35,37 but the CM was unknown in the other cases. 36,38 Iopromide in addition to iomeprol was also found to cause SDRIFE in one patient on two separate occasions. 35 In another patient with unknown CM exposure, intravenous controlled challenge was positive to iomeprol, iopamide and ioversol, demonstrating crossreactivity amongst monomeric nonionic CM.…”

“…35 In another patient with unknown CM exposure, intravenous controlled challenge was positive to iomeprol, iopamide and ioversol, demonstrating crossreactivity amongst monomeric nonionic CM. 38 Graft-versus-host disease secondary to iodinated contrast media Three patients with successful allogenic bone marrow transplantation developed cutaneous graft-versus-host disease (GvHD) to nonionic dimer CM (Table 5). 39 All patients had prior GvHD, and the authors suggested that immune complexes could have triggered or precipitated already present or latent cutaneous GvHD.…”