Recurrent staphylococcal infection in families

Abstract

This controlled double-blind study examined the efficacy of a single large inoculum of Staphylococcus aureus 502A in interrupting intrafamilial spread of recurrent staphylococcal abscesses. Forty families were enrolled in the study and 32 completed six months of follow-up care. All participants were first treated with oral oxacillin sodium or dicloxacillin sodium, twice daily hexachlorophene showers, and bacitracin given nasally for two weeks. Some then received nasal

Cultivation of Epithelial-Associated Microbiota by The Immune System

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Cultivation of Epithelial-Associated Microbiota by The Immune System

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Impetigo: An Overview

“…Competitive binding to cell surface receptors by resident flora or transient flora of low virulence may also prevent pathogenic bacteria from colonizing the skin. A nonvirulent strain of 5. aureus has been useful in neonates during nursery epidemics to prevent colonization of the nasal mucosa with a pathogenic strain of S. aureus (20), and in adults to prevent spread of recurrent staphylococcal abscesses within families (21).…”

Cultivation of Epithelial-Associated Microbiota by The Immune System

“……”

Impetigo: An Overview

“…Competitive binding to cell surface receptors by resident flora or transient flora of low virulence may also prevent pathogenic bacteria from colonizing the skin. A nonvirulent strain of 5. aureus has been useful in neonates during nursery epidemics to prevent colonization of the nasal mucosa with a pathogenic strain of S. aureus (20), and in adults to prevent spread of recurrent staphylococcal abscesses within families (21).…”

Cultivation of Epithelial-Associated Microbiota by The Immune System

“……”

Impetigo: An Overview

“…Competitive binding to cell surface receptors by resident flora or transient flora of low virulence may also prevent pathogenic bacteria from colonizing the skin. A nonvirulent strain of 5. aureus has been useful in neonates during nursery epidemics to prevent colonization of the nasal mucosa with a pathogenic strain of S. aureus (20), and in adults to prevent spread of recurrent staphylococcal abscesses within families (21).…”