Recurrent, Pruritic Dermal Plaques and Bullae—Quiz Case

Green, W. Harris; Yosipovitch, Gil; Pichardo, Rita O

doi:10.1001/archderm.143.6.791-b

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Cited by 11 publications

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“…Wells’ syndrome is rarely present with systemic involvement, but eosinophilia is common [7]. Peripheral eosinophilia was found in half of the cases as well as in our patient, but it is not required for diagnosis [6, 7]. …”

Section: Discussionmentioning

confidence: 72%

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Eosinophilic cellulitis (Wells’ syndrome) caused by a temporary henna tattoo

Nacaroğlu¹,

Çeleğen²,

Karkıner³

et al. 2014

pdia

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Eosinophilic cellulitis (Wells’ syndrome) is an uncommon condition of unknown etiology. Wells’ syndrome is usually seen in adulthood but very rare in childhood. Although pathogenesis of the disease is not very clear, it is a hypersensitivity reaction developing against a variety of exogenous and endogenous antigenic stimuli. Paraphenylenediamine is a strong allergen frequently used as a temporary henna tattoo, which makes the color darker. Here, a 9-year-old male patient with Wells’ syndrome is presented, which developed following a temporary henna tattoo and shown by the patch test sensitivity to paraphenylenediamine.

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Section: Discussionmentioning

confidence: 72%

“…Pruritus can be intractable and unresponsive to anti-histamines. Affected individuals typically present with erythematous plaques over a 2- to 3-day period and plaques usually resolve without scarring over 2–8 weeks [6]. During this period, pale and atrophic skin lesions may be confused with symptoms of morphea disease [3–6].…”

Section: Discussionmentioning

confidence: 99%