Recurrent non-Q-wave myocardial infarction associated with toluene abuse

Dilated Cardiomyopathy Associated with Toluene Abuse

“…Recurrent ventricular fibrillation resistant to defibrillation and antiarrhythmic treatment was reported [13,14,15]. We hypothesized that toluene exerted direct cardiotoxic effects.…”

“…Myocardial function had obviously returned to normal ranges in the absence of spasm. On the contrary, recurrent non-Q wave infarction associated with toluene inhalation may obviously result in permanent myocardial damage [15]. …”

“…Cardiotoxicity, e.g. arrhythmia, sudden death, myocardial infarction [13,14,15], cardiomyopathy [16] and fatal acute myocarditis [17], has often been ignored.…”

Cardiovascular Toxicology

“…383,2 Poisonings comprise the majority of reports on toluene toxicity (407,408). A case of recurrent non-Q-wave myocardial infarction was reported in a 55-year-old toluene abuser (412). Research pertaining to toluene-induced cardiomyopathy is lacking.…”

Recreational drug misuse: issues for the cardiologist

“…In some instances, myocardial ischaemia and infarction can be produced by coronary vasospasm, a reduction in the oxygen carrying capacity of the blood related to the formation of carboxyhaemoglobin or methaemoglobinaemia, or excessive sympathetic stimulation 5759-63 Chronic misuse of some volatile substances can induce a poorly characterised cardiomyopathy 6064 …”