Recurrent Lecythophora mutabilis Keratitis and Endophthalmitis After Deep Anterior Lamellar Keratoplasty

Coniochaeta massiliensis sp. nov. Isolated from a Clinical Sampl28

“…Antifungal susceptibility testing showed relatively low MICs for AMB, 5-FC, ITC, POS, and VOR in all strains. These results are in line with those of Perdomo et al (2011) but contrast with those of other authors [ 9 , 13 , 20 ] who reported relatively high MICs for AMB and ITC against C. hoffmannii and C. mutabilis.…”

Coniochaeta massiliensis sp. nov. Isolated from a Clinical Sampl28

“…Antifungal susceptibility testing showed relatively low MICs for AMB, 5-FC, ITC, POS, and VOR in all strains. These results are in line with those of Perdomo et al (2011) but contrast with those of other authors [ 9 , 13 , 20 ] who reported relatively high MICs for AMB and ITC against C. hoffmannii and C. mutabilis.…”

Coniochaeta mutabilis keratitis with an unusual mode of transmission treated with penetrating keratoplasty and systemic antifungals

“… 6 , 7 In this case, the corneal filaments growing around the original lesion appeared to be endothelial. A similar pattern might have been the reason why DALK failed in the case reported by Fintelmann et al 3 As an alternative, conjunctival flaps have proven to be a prominent procedure in the management of severe fungal keratitis, offering a transitional opportunity in situations where a transplant is not readily available. 8 , 9 …”

“…In all reported cases, the course of disease tended to be very aggressive in nature, and in one case the infection recurred after transplantation with a partial-thickness graft. 3 Antifungal susceptibility profiles varied in each case, showing that the species does not carry a consistent antifungal response.…”

A rare case of Lecythophora endogenous endophthalmitis: Diagnostic and therapeutic challenge

“…Ocular involvement by Lecythophora has been reported in the form of bleb-related endophthalmitis,[ 5 ] after corneal cyanoacrylate glue application and after deep anterior lamellar keratoplasty. [ 6 7 ] Lecythophora is a mold that lacks a known sexual state and is thus categorized under Fungi Imperfecti. It is generally classified as a dematiaceous fungus which is mainly attributed to its darkly colored fungal body due to the presence of melanin in the cell walls of its conidia, hyphae, or both and is ubiquitous in nature.…”

“…[ 4 ] While Candida and Aspergillus are the most common species among fungal causes of EE, Lecythophora has been rarely reported as a cause of endophthalmitis due to exogenous causes. [ 5 6 7 8 ] We, herein, report a case of EE caused by Lecythophora species.…”

Coniochaeta massiliensis sp. nov. Isolated from a Clinical Sampl28

“…Antifungal susceptibility testing showed relatively low MICs for AMB, 5-FC, ITC, POS, and VOR in all strains. These results are in line with those of Perdomo et al (2011) but contrast with those of other authors [ 9 , 13 , 20 ] who reported relatively high MICs for AMB and ITC against C. hoffmannii and C. mutabilis.…”

Coniochaeta mutabilis keratitis with an unusual mode of transmission treated with penetrating keratoplasty and systemic antifungals

“… 6 , 7 In this case, the corneal filaments growing around the original lesion appeared to be endothelial. A similar pattern might have been the reason why DALK failed in the case reported by Fintelmann et al 3 As an alternative, conjunctival flaps have proven to be a prominent procedure in the management of severe fungal keratitis, offering a transitional opportunity in situations where a transplant is not readily available. 8 , 9 …”

“…In all reported cases, the course of disease tended to be very aggressive in nature, and in one case the infection recurred after transplantation with a partial-thickness graft. 3 Antifungal susceptibility profiles varied in each case, showing that the species does not carry a consistent antifungal response.…”

A rare case of Lecythophora endogenous endophthalmitis: Diagnostic and therapeutic challenge

“…Ocular involvement by Lecythophora has been reported in the form of bleb-related endophthalmitis,[ 5 ] after corneal cyanoacrylate glue application and after deep anterior lamellar keratoplasty. [ 6 7 ] Lecythophora is a mold that lacks a known sexual state and is thus categorized under Fungi Imperfecti. It is generally classified as a dematiaceous fungus which is mainly attributed to its darkly colored fungal body due to the presence of melanin in the cell walls of its conidia, hyphae, or both and is ubiquitous in nature.…”

“…[ 4 ] While Candida and Aspergillus are the most common species among fungal causes of EE, Lecythophora has been rarely reported as a cause of endophthalmitis due to exogenous causes. [ 5 6 7 8 ] We, herein, report a case of EE caused by Lecythophora species.…”

Coniochaeta massiliensis sp. nov. Isolated from a Clinical Sampl28

“…Antifungal susceptibility testing showed relatively low MICs for AMB, 5-FC, ITC, POS, and VOR in all strains. These results are in line with those of Perdomo et al (2011) but contrast with those of other authors [ 9 , 13 , 20 ] who reported relatively high MICs for AMB and ITC against C. hoffmannii and C. mutabilis.…”

Coniochaeta mutabilis keratitis with an unusual mode of transmission treated with penetrating keratoplasty and systemic antifungals

“… 6 , 7 In this case, the corneal filaments growing around the original lesion appeared to be endothelial. A similar pattern might have been the reason why DALK failed in the case reported by Fintelmann et al 3 As an alternative, conjunctival flaps have proven to be a prominent procedure in the management of severe fungal keratitis, offering a transitional opportunity in situations where a transplant is not readily available. 8 , 9 …”

“…In all reported cases, the course of disease tended to be very aggressive in nature, and in one case the infection recurred after transplantation with a partial-thickness graft. 3 Antifungal susceptibility profiles varied in each case, showing that the species does not carry a consistent antifungal response.…”

A rare case of Lecythophora endogenous endophthalmitis: Diagnostic and therapeutic challenge

“…Ocular involvement by Lecythophora has been reported in the form of bleb-related endophthalmitis,[ 5 ] after corneal cyanoacrylate glue application and after deep anterior lamellar keratoplasty. [ 6 7 ] Lecythophora is a mold that lacks a known sexual state and is thus categorized under Fungi Imperfecti. It is generally classified as a dematiaceous fungus which is mainly attributed to its darkly colored fungal body due to the presence of melanin in the cell walls of its conidia, hyphae, or both and is ubiquitous in nature.…”

“…[ 4 ] While Candida and Aspergillus are the most common species among fungal causes of EE, Lecythophora has been rarely reported as a cause of endophthalmitis due to exogenous causes. [ 5 6 7 8 ] We, herein, report a case of EE caused by Lecythophora species.…”