Rectosigmoid adenocarcinoma revealed by metastatic anal fistula. The visible part of the iceberg: a report of two cases with literature review

Benjelloun, El Bachir; Aitalalim, Said; Chbani, Leila; Mellouki, I.; Mazaz, Khalid; Aittaleb, K.

doi:10.1186/1477-7819-10-209

Cited by 22 publications

(33 citation statements)

References 20 publications

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“…These have a well‐recognized role in anastomotic recurrence , suture line implantation and seeding onto stapling devices . Rarely, colorectal adenocarcinoma cells can implant into the tracks of a fistula‐in‐ano (Table ), haemorrhoidectomy scars and other miscellaneous sites of anal trauma .…”

Section: Introductionmentioning

confidence: 99%

Endoscopic excision of synchronous large bowel polyps in the presence of colorectal carcinoma: is the fear of malignant cell implantation justified? A systematic review of the literature

Sheel

Artioukh

2015

Colorectal Disease

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Section: Introductionmentioning

confidence: 99%

Endoscopic excision of synchronous large bowel polyps in the presence of colorectal carcinoma: is the fear of malignant cell implantation justified? A systematic review of the literature

Sheel

Artioukh

2015

Colorectal Disease

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“…There are 27 reported cases of implantation of colon cancer in an anal fistula, which include cases previously encountered by the current authors [14–16]. In most of those cases, the primary tumor was found in the sigmoid colon or the rectum (2 in the descending colon, 13 in the sigmoid colon, 10 in the upper rectum, and 2 in the lower rectum).…”

Section: Discussionmentioning

confidence: 69%

A case of metastatic carcinoma of anal fistula caused by implantation from rectal cancer

et al. 2015

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This case involved an 80-year-old man who was seen for melena. Further testing revealed a tubular adenocarcinoma 50 mm in size in the rectum. In addition, an anal fistula was noted behind the anus along with induration. A biopsy of tissue from the external (secondary) opening of the fistula also revealed adenocarcinoma. Nodules suspected of being metastases were noted in both lung fields. The patient was diagnosed with rectal cancer, a cancer arising from an anal fistula, and a metastatic pulmonary tumor, and neoadjuvant chemotherapy was begun. A laparoscopic abdominoperineal resection was performed 34 days after 6 cycles of mFOLFOX-6 therapy. Based on pathology, the rectal cancer was diagnosed as moderately differentiated adenocarcinoma, and this adenocarcinoma had lymph node metastasis (yp T3N2aM1b). There was no communication between the rectal lesion and the anal fistula, and a moderately differentiated tubular adenocarcinoma resembling the rectal lesion was noted in the anal fistula. Immunohistochemical staining indicated that both the rectal lesion and anal fistula were cytokeratin 7 (CK7) (−) and cytokeratin 20 (CK20) (+), and the patient’s condition was diagnosed as implantation of rectal cancer in an anal fistula.In instances where an anal fistula develops in colon cancer, cancer implantation in that fistula must also be taken into account, and further testing should be performed prior to surgery.

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“…Sex prevalence is important as most cases that were reported were male patients except one female. A histological examination should be performed in all cases of long standing fistula and perianal abscess (3)(4)(5) . In 1907 Charles Ryall (5) was the first to report the phenomenon known as cancer infection which is implantation metastasis of solid cancers (3,6) .…”

Section: Discussionmentioning

confidence: 99%

Rectosigmoid Adenocarcinoma That Is Synchronous with an Anal Fistula : Case Report in Saudi Arabia

AlYousef

Hakami

Wtayyan

et al. 2018

Egyptian Journal of Hospital Medicine

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Rectosigmoid mucinous adenocarcinoma that is Synchronous with an anal fistula is a very rare condition thus its diagnosis and management are challenging. Here, we showed the diagnosis and management of a single case for a 57-year-old Saudi male presented with low rectal mass and gluteal abscess and a history of recurrent perianal abscesses that was managed as benign tumor and without a family history of neoplasms of re colorectal parts. After reviewing the literature concerning the aetiopathogenesis of this case and the suggested treatment. The clinical examination showed a perianal fistula and a digital rectal examination was conducted after incision and drainage of the right gluteal abscess then rigid sigmoidoscopy was performed and biopsy was collected showing invasive moderately differentiated adenocarcinoma. The decision was to avoid radiation preoperative due to abscess and extensive perianal disease and a treatment plan was initiated and the patient was followed up with regular CT examination.

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Rectosigmoid adenocarcinoma revealed by metastatic anal fistula. The visible part of the iceberg: a report of two cases with literature review

Cited by 22 publications

References 20 publications

Endoscopic excision of synchronous large bowel polyps in the presence of colorectal carcinoma: is the fear of malignant cell implantation justified? A systematic review of the literature

Endoscopic excision of synchronous large bowel polyps in the presence of colorectal carcinoma: is the fear of malignant cell implantation justified? A systematic review of the literature

A case of metastatic carcinoma of anal fistula caused by implantation from rectal cancer

Rectosigmoid Adenocarcinoma That Is Synchronous with an Anal Fistula : Case Report in Saudi Arabia

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