Rectal indomethacin use in pain relief during hysterosalpingography: A randomized placebo controlled trial

Karaman, Erbil; Çim, Numan; Alkış, İsmet; Yıldırım, Abdullah; Yıldızhan, Recep

doi:10.1111/jog.12863

Cited by 10 publications

(14 citation statements)

References 21 publications

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“…Two studies were excluded: one because was related to the comparison of two different modes of lignocaine (spray and jelly) 13 and another one was not a randomized controlled trial. 14 Sixteen randomized controlled trials 3 , 6 , 15 - 18 , 22 , 23 , 28 were considered as primary relevant studies and included in this network meta-analysis.…”

Section: Resultsmentioning

confidence: 99%

“…Of the sixteen randomized controlled trials analyzed, Cochrane Collaboration tool indicated that ten trials 15 - 19 , 22 , 24 - 27 used an adequate randomization and three trials 3 , 18 , 22 used an adequate allocation concealment. Five studies 3 , 17 , 18 , 22 , 24 reported adequate blinding and seven studies 3 , 16 , 19 , 23 , 24 , 26 , 27 were free of selective reporting. Ten trials 3 , 16 - 18 , 20 - 23 , 25 , 27 reported incomplete outcome data ( Table-II ).…”

Section: Resultsmentioning

confidence: 99%

“…Five studies 3 , 17 , 18 , 22 , 24 reported adequate blinding and seven studies 3 , 16 , 19 , 23 , 24 , 26 , 27 were free of selective reporting. Ten trials 3 , 16 - 18 , 20 - 23 , 25 , 27 reported incomplete outcome data ( Table-II ).…”

Section: Resultsmentioning

confidence: 99%

“… 1 Therefore, it is crucial to assess fallopian tubes patency during the diagnosis of infertility. 2 Hysterosalpingography (HSG) is considered as the gold standard in the assessment of tubal patency 3 and it is also recommended by the National Institute for Health and Care Excellence (NICE) guidelines for tubal occlusion evaluation in the absence of co-morbidities. 4…”

Section: Introductionmentioning

confidence: 99%

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Effectiveness of interventions for pain relief in hysterosalpingography: A network meta-analysis and systematic review

Guo

Tan

2017

Pak J Med Sci

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Objective:We aimed to evaluate the effectiveness of placebo, oral opioid analgesic (OOA), intravenous opioid analgesic (IOA), non-opioid analgesic (NOA), topical anesthetic (TA) and locally injected anesthetic (LIA) for pain relief duringhysterosalpingography (HSG) using a Bayesian network meta-analysis of data from randomized controlled trials.Methods:PUBMED, EMBASE, and CENTRAL search engines were used to search and identify clinical trials that evaluated interventions for pain relief in HSG. Methodological studies quality was assessed by the Cochrane Collaboration tool for assessing risk of bias.Result:Sixteen trials involving 1263 participants were included in this study. IOA got excess but not statistically significant lower visual analogue score (VAS) pain score during HSG or more than 30 minutes after HSG compared with the other groups. OOA resulted in excess but not statistically significant higher VAS pain score during HSG compared with the other groups except placebo group. According to SUCRA regarding the lower VAS pain score during HSG, the treatments rank was the following: IOA, TA, NOA, LIA, OOA and placebo; as regard lower VAS pain score at 30 minutes or more after HSG, the treatments rank was the following: IOA, LIA, OOA, TA, NOA and placebo.Conclusion:This new Bayesian data network meta-analysis from randomized controlled trials demonstrated that IOA resulted in the highest probability to reduce the pain during HSG or at 30 minutes or more after HSG among the six interventions considered.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effectiveness of interventions for pain relief in hysterosalpingography: A network meta-analysis and systematic review

Guo

Tan

2017

Pak J Med Sci

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“…The procedure is moderately invasive and exposes patients to ionizing radiation, and other (allergies) risks inherent to the use of iodinated contrast media. In addition, women may present with discomfort (pain) during and immediately after the procedure, and in rare cases, may lead to the dissemination of an underlying undiagnosed infection into the peritoneal cavity [10].…”

Section: Introductionmentioning

confidence: 99%

Findings of Hysterosalpingography in Women Who Underwent Gynaecologic Imaging in a Tertiary Hospital in Douala, Cameroon

Egbe¹,

Ngombiga²,

Takang³

et al. 2020

ARSci

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Background: Hysterosalpingography (HSG) is the first-line investigation among infertile women in Cameroon. There is a dearth of studies on the use of HSG in Cameroon. The aim of this study was threefold: 1) to describe the indications; 2) findings of hysterosalpingography and 3) factors associated with abnormal findings on HSG at the Douala General Hospital, Cameroon. Methods: We conducted a retrospective descriptive study of 242 files of patients who underwent hysterosalpingography at the Radiology Department of the Douala General Hospital from January 2012 to December 2016. We collected data on the sociodemographic, obstetric variables and indications of HSG using a pretested data collection form. We also interpreted HSG films during the study period. Data analysis was with EPI-INFO version 7. Results: The age range was 19-46 years with a mean age of 33.16 ± 5.45 years. Majority 138/242 (57.1%) were in the age group 30-40 years. The main indication of HSG was infertility 87.2% (211/242). Most of the cases 95.87% (232/242) had abnormal findings at HSG. Tubal and uterine abnormal findings made up 133/232 (57.3%), and 97/232 (41.81%) of cases, respectively. Tubal occlusion and hydrosalpinges were found in 99/232 (42.67%) and 19/232 (8.19%) while uterine fibroids and uterine synechiae were found in 57/232 (24.97%) and 30/232 (12.93%), respectively. The factors independently associated with abnormal findings at HSG were: a history of recurrent pregnancy loss (AOR 2.95; 95% CI: 1.19-7.32, p = 0.02) and infertility (AOR 0.24; 95%

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Effect of oral diclofenac potassium plus cervical lidocaine cream on pain perception during hysterosalpingography: A randomized, double-blind, placebo-controlled trial

Abbas

Wagdy

Salem

et al. 2018

Middle East Fertility Society Journal

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Rectal indomethacin use in pain relief during hysterosalpingography: A randomized placebo controlled trial

Abstract: Our study demonstrated a significant reduction in pain in patients who received a single rectal dose of indomethacin; therefore, we recommend the use of rectal indomethacin for reducing pain during a HSG procedure.

Cited by 10 publications

References 21 publications

Effectiveness of interventions for pain relief in hysterosalpingography: A network meta-analysis and systematic review

Effectiveness of interventions for pain relief in hysterosalpingography: A network meta-analysis and systematic review

Findings of Hysterosalpingography in Women Who Underwent Gynaecologic Imaging in a Tertiary Hospital in Douala, Cameroon

Effect of oral diclofenac potassium plus cervical lidocaine cream on pain perception during hysterosalpingography: A randomized, double-blind, placebo-controlled trial

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