Reconstruction of artificial nuclei with nuclear import activity in living mouse oocytes
Nao Yonezawa,
Tomoko Shindo,
Haruka Oda
et al.
Abstract:The cell nucleus is a dynamic structure repeating disassembly and reformation during mitosis. Reformation of the nucleus is essential for cell proliferation, and therefore, the factors required for nuclear reformation are fundamental for eukaryotes. Although various factors have been identified in in vitro systems using frog egg extracts and in vivo imaging of somatic cells, little is known about the factors required for the formation of functional nuclear structures in living mouse eggs. To identify such fact… Show more
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