Recognizing Depression in the Elderly: Practical Guidance and Challenges for Clinical Management

Devita, Maria; Salvo, Rossella De; Ravelli, Adele; Rui, Marina De; Coin, Alessandra; Sergi, Giuseppe; Mapelli, Daniela

doi:10.2147/ndt.s347356

Cited by 22 publications

(17 citation statements)

References 80 publications

(135 reference statements)

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“…However, this rate escalates with advancing age, reaching its peak at 27% among individuals over 85 years of age. [36] In a study conducted with 271 patients, it was found that participants aged over 80 were at a higher risk of depression compared to those under 80. [37] The prevalence of depression and anxiety among cancer patients is statistically significant higher compared to the general population.…”

Section: Discussionmentioning

confidence: 99%

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Risks of undernutrition and depression in hospitalized patients: A cross-sectional study

Asma,

Tuncer

2023

Medicine

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Undernutrition in hospitalized patients is a significant healthcare burden worldwide. Depression is a major global health problem characterized by symptoms such as altered mood, loss of interest and pleasure, and impairment in cognitive and physical functions. Patients hospitalized for medical conditions have a higher risk of depression than the general population. The purpose of this study was to explore the relationship between undernutrition risk and depression risk in hospitalized patients. The design of this study was an observational cross-sectional analytic. A questionnaire form created by the investigator including sociodemographic data, dietary patterns, presence of chronic diseases and anthropometric measurements, Nutritional Risk Screening and Patient Health Questionnaire-2 were applied to the patients. All quantitative data were expressed as the median and interquartile range and qualitative data were expressed as numbers and percentage. Mann–Whitney U test and Kruskal–Wallis test were used to analyze nonparametric data; Chi-square and Fisher Exact test were used to analyze qualitative data. P < .05 was considered statistically significant. A total of 308 patients who met the criteria were reached. Undernutrition was detected in 28.6% of the participants, and depression was present in 37.3%. A statistically significant relationship was found between the risk of undernutrition and the risk of depression, with individuals without a risk of depression being found to have a lower risk of undernutrition. (P < .001). The risk of undernutrition was found to increase with advancing age. Moreover, individuals with higher values for arm muscle area, arm muscle circumference, mid-upper arm circumference, triceps skinfold thickness, calf circumference, and body mass index had a lower risk of undernutrition. No relationship was found between gender and the risk of depression. However, a statistically significant relationship was observed between age and the risk of depression, indicating that older patients had a higher risk of depression. In this study, a statistically significant relationship was found between the risk of undernutrition and the risk of depression in hospitalized patients. It was observed that the risk of undernutrition was lower in individuals without risk of depression.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Risks of undernutrition and depression in hospitalized patients: A cross-sectional study

Asma,

Tuncer

2023

Medicine

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“…However, switches in diet, as well as advancing age, cause changes in the number of individual genera. For example, an increase in the abundance of the bile-tolerant species from the Bacteroidetes phylum belonging to such genera as Bacteroides and Alistipes , and Bilophila from the Proteobacteria , and a decrease in Firmicutes are associated with protein- and fat-enriched diet [ 62 ]. In turn, the gut microbiota of the elderly is characterized by a decreased Bacteroides to Firmicutes ratio, and most of all, reduced Bifidobacterium abundance, amylolytic activity, and SCFA production as well as an increase in the abundance of Gram-negative rods from Enterobacteriaceae .…”

Section: Intestinal Microbiotamentioning

confidence: 99%

The Role of Probiotics and Their Metabolites in the Treatment of Depression

et al. 2023

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Depression is a common and complex mental and emotional disorder that causes disability, morbidity, and quite often mortality around the world. Depression is closely related to several physical and metabolic conditions causing metabolic depression. Studies have indicated that there is a relationship between the intestinal microbiota and the brain, known as the gut–brain axis. While this microbiota–gut–brain connection is disturbed, dysfunctions of the brain, immune system, endocrine system, and gastrointestinal tract occur. Numerous studies show that intestinal dysbiosis characterized by abnormal microbiota and dysfunction of the microbiota–gut–brain axis could be a direct cause of mental and emotional disorders. Traditional treatment of depression includes psychotherapy and pharmacotherapy, and it mainly targets the brain. However, restoration of the intestinal microbiota and functions of the gut–brain axis via using probiotics, their metabolites, prebiotics, and healthy diet may alleviate depressive symptoms. Administration of probiotics labeled as psychobiotics and their metabolites as metabiotics, especially as an adjuvant to antidepressants, improves mental disorders. It is a new approach to the prevention, management, and treatment of mental and emotional illnesses, particularly major depressive disorder and metabolic depression. For the effectiveness of antidepressant therapy, psychobiotics should be administered at a dose higher than 1 billion CFU/day for at least 8 weeks.

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“…In dementia, symptoms tend to have a slower onset, while depression symptoms typically manifest more rapidly [34]. Another important clue is that patients with depression often complain more about cognitive impairments, whereas individuals with dementia frequently deny any memory complaints and state that they sought medical attention because of their family's concerns [35]. In this case, the patient's family could not provide precise information about the onset of the patient's symptoms, but the patient did not have significant complaints, and it was their family who brought them to the hospital.…”

Section: Appraisalmentioning

confidence: 99%

One Patient, Three Providers: A Multidisciplinary Approach to Managing Common Neuropsychiatric Cases

Özge,

Domaç,

Tekin

et al. 2023

JCM

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Background: Neuropsychiatric cases require a multidisciplinary approach for effective management. This paper presented case-based discussions on migraine, dementia, epilepsy, mood disorders, neuralgia, and psychosis from the perspectives of a family physician, neurologist, and psychiatrist. The goal was to highlight the importance of collaboration between healthcare providers in managing these complex cases. Methods: The paper was based on the proceedings of the Mediterranean Neuropsychiatry Symposium, where experts from family medicine, neurology, and psychiatry came together for comprehensive case-based discussions. The CARE framework (Case Report, Appraisal, Research, and Education) was developed to guide reporting and evaluation of case reports in clinical practice. Results: Six cases were presented and discussed, highlighting the importance of a multidisciplinary approach in managing neuropsychiatric cases. The cases included chronic migraine with medication overuse, memory dysfunction with language and behavioral problems, refractory epileptic seizures with subjective sensory symptoms, bipolar affective disorder with normal pressure hydrocephalus, postherpetic neuralgia in a case with bipolar affective disorder, and psychosis with recurrent attacks with the abuse of several substances. Conclusion: A biopsychosocial multidisciplinary approach is essential for managing neuropsychiatric cases effectively on behalf of the patients and public health of the country. The CARE framework can guide the reporting and evaluation of case reports in clinical practice, ensuring that patients receive comprehensive and effective care. Healthcare providers should collaborate to provide the best possible care for patients with complex and multifaceted needs.

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Recognizing Depression in the Elderly: Practical Guidance and Challenges for Clinical Management

Cited by 22 publications

References 80 publications

Risks of undernutrition and depression in hospitalized patients: A cross-sectional study

Risks of undernutrition and depression in hospitalized patients: A cross-sectional study

The Role of Probiotics and Their Metabolites in the Treatment of Depression

One Patient, Three Providers: A Multidisciplinary Approach to Managing Common Neuropsychiatric Cases

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