volume 66, issue 6, P3643-3651 1992
DOI: 10.1128/jvi.66.6.3643-3651.1992
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V Litwin, W Jackson, C Grose

Abstract: The varicella-zoster virus (VZV) genome contains 70 reading frames (ORF), 5 of which encode the glycoproteins gpl, gpII, gpIII, gprV, and gpV. ORF 67 and 68 lie adjacent to each other in the unique short region of the VZV genome and code for gpIV and gpl, respectively. These two genes, which are contained within the HindIII C fragment of the VZV genome, were subcloned in the correct orientation downstream from the promoter regions of the eukaryotic expression vectors pCMV5 and pBJ. After transfection, 5 to 20%…

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