Receptor Potential of Vertebrate Retina

Motokawa, Köiti; Oikawa, Takahiro; Tasaki, Kyoji

doi:10.1152/jn.1957.20.2.186

Cited by 53 publications

(17 citation statements)

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“…Similar records have been obtained by Motokawa, Oikawa & Tasaki (1957), Tomita (1957), Tomita, Tosaka, Watanabe & Sato (1958), Griisser (1957 and Brown & Wiesel (1958), the latter two from the eye of the cat.…”

supporting

confidence: 82%

Excitation pools in the frog's retina

Rushton¹

1959

The Journal of Physiology

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The pioneer work of Granit (1942) showed that a single ganglion cell in the frog's retina was not always connected to one type of receptor. The studies described in our three preceding papers (Donner & Rushton, 1959a, b;Donner, 1959) were undertaken to explore further the connexion between ganglion cells and the different types of receptor. It was clear that if in any given state only one type of photoreceptor was connected, stimulation by substitution would exhibit three characteristics. (a) A silent substitution could always be achieved if the intensity of the new light was correctly chosen, the correct intensity (in quanta/sec) for each wave-length varying inversely as the absorption at that wave-length by the visual pigment involved. (b) The Fechner fraction, that is the logarithmic range of intensities over which the substitution remained silent, must be constant whatever wavelength was involved. (c) Adaptation to any colour which did not alter the connexion between receptor and ganglion would leave the spectral sensitivity of silent substitution unchanged.The results of our first paper (Donner & Rushton, 1959 a) showed that some ganglion cells did not exhibit silent substitution, and hence must have been connected to more than one type of receptor at the same time. This was a complexity which we wished to avoid, and so we chose only those cells which did respond usually by silence when the substituted intensity was properly adjusted. Even these cells failed in a restricted range of intensity just below the level where the photopic dominator curve is obtained. But in the photopic range the results were consistent with the idea that ganglion cells are connected to a single class of receptors (cones) whose visual pigment absorbs according to Granit's (1942) photopic dominator curve: in full dark adaptation they are connected to other cells (rods) whose sensitivity corresponds to rhodopsin, and in changing from dark to mesopic adaptation there is a gradual change from the pure rhodopsin sensitivity to one with 'humps' in the green and in the blue, but with the characteristics (a, b, c) above still maintained. A formal explanation could be that some inert screening pigment 22PHYSIO. CXLIX

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supporting

confidence: 82%

Excitation pools in the frog's retina

Rushton¹

1959

The Journal of Physiology

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“…4 a, b, c). Other investigators, however, have recorded a reversal of response polarity when these units were penetrated in fish (Motokawa et al 1957;MacNichol & Svaetichin, 1958 (1956,1958) describes a membrane in frog and rat retinas which has a high radial resistance relative to the resistance of the rest of the retina and choroid. He calls this the 'R membrane', to designate a membrane of high electrical resistance without identifying it with a specific structure.…”

Section: -8 Sec U_idmentioning

confidence: 99%

“…In the cat retina Motokawa et al (1957) and Griisser (1957) have recorded from units which yield only slow potentials. These responses have been called 'receptor potentials', referring to Svaetichin's early work on fish.…”

Section: Response Patterns Of Single Units Which Discharge Impulsesmentioning

confidence: 99%

Intraretinal recording with micropipette electrodes in the intact cat eye

Brown¹,

Wiesel²

1959

The Journal of Physiology

120

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“…1). When the retina was subjected to intermittent illumina- Motokawa et al 4) showed that there are two types of elements, N and A, in the carp retina.…”

Section: Resultsmentioning

confidence: 99%

“…Although this potential was at first supposed to originate in a cone, it was doubted by various investiga tors3, 4,5) Recently it has been shown by Oikawa, Ogawa and Motokawa6) that this potential has its origin in a secondary neuron of the retina. As to the mechanism of flicker fusion some authors stress the im portance of the peripheral mechanism, but others that of the central mechanism.…”

Section: Svaetichin1mentioning

confidence: 97%