Recent developments in green membrane-based extraction techniques for pharmaceutical and biomedical analysis

Tabani, Hadi; Nojavan, Saeed; Alexovič, Michal; Sabó, Ján

doi:10.1016/j.jpba.2018.08.002

Cited by 69 publications

(8 citation statements)

References 241 publications

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“…The SERS intensity at 1649 cm –1 increased with increasing R6G concentration (Figure B), and even if only 10 –7 M R6G was added to the peel surface, the SERS signal could still be identified (Figure C). Compared with traditional extraction methods such as microwave-assisted extraction (MAE), accelerated solvent extraction (ASE), and membrane extraction, this method is time-saving, labor-saving, simple to operate, and low-cost. − Encouragingly, the Ag NWs@LIG@PDMS is flexible and durable, so it does not damage the samples and can be reused. It achieves fast, effective, and nondestructive target extraction from the original complex object surface, which is of great significance in analytical science.…”

Section: Resultsmentioning

confidence: 99%

Flexible and Highly Sensitive Sandwich-Structured PDMS with Silver Nanowires and Laser-Induced Graphene for Rapid Residue Detection

Cheng

Qian

Ruan

et al. 2023

ACS Appl. Polym. Mater.

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Flexible surface-enhanced Raman scattering (SERS) substrates offer advantages over traditional rigid substrates for efficient extraction of target molecules from complex surfaces, which is critical for technical applications ranging from pesticide residue analysis to environmental pollutant monitoring and forensic science detection. Herein, flexible sandwich-structured silver nanowires with laser-induced graphene and polydimethylsiloxane (PDMS) (Ag NWs@LIG@PDMS) with high SERS activity, flexibility, and stability were prepared by a simple method. Its detection limit is as high as 10–14 M, which is significantly higher than that of silver nanowires embedded in PDMS (Ag NWs/PDMS) and silver nanowire adhesive PDMS (Ag NWs@PDMS) with bilayer structure, due to the efficacy of interlayer laser-induced graphene (LIG). Moreover, compared with similar structures, the sophisticated structural design of silver nanowires with laser-induced graphene embedded in PDMS (Ag NWs/LIG@PDMS) enables higher SERS activity. Apart from this, the Ag NWs@LIG@PDMS film maintains excellent SERS performance even under 10% tensile deformation and extreme operating temperature (−80 to 80 °C). In view of the above-mentioned advantages, SERS substrates have been successfully used for fast, efficient, low-cost, and nondestructive extraction and detection of peel surface and fingerprint residues in real scenes, providing avenues for molecular trace extraction and detection in food safety and forensics science.

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Section: Resultsmentioning

confidence: 99%

Flexible and Highly Sensitive Sandwich-Structured PDMS with Silver Nanowires and Laser-Induced Graphene for Rapid Residue Detection

Cheng

Qian

Ruan

et al. 2023

ACS Appl. Polym. Mater.

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“…Spectral chromatography contains a large profile of information that can be used beneficially by using multivariate mathematical and statistical (stoichiometric) techniques to discuss a comprehensive exploration of collected data and experimental results established for quantitative (calibration) and qualitative purposes. 27 Novel "green" analysis methods (keeping the requirements of green pharmaceutical analytical chemistry) are introduced to achieve effective, economic and environmental experimental goals, 28 so as to stimulate students to explore the subjective initiative of knowledge. The effect of online case teaching adopts two evaluation indexes, which are subjective and objective.…”

Section: Discussionmentioning

confidence: 99%

Application of the Case Teaching Method in a Pharmaceutical Analysis Online Course

Ni¹,

Guo²,

Chen³

et al. 2023

Ind. J. Pharm. Edu. Res.

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Objectives: To explore the teaching effect of integrating the case teaching method into an online course on pharmaceutical analysis. Materials and Methods: The case teaching method was adopted as the technique for delivering professional knowledge. The online course integrated knowledge teaching, practical ability, and value guidance. The effect of the case teaching method was evaluated by course assessment and a questionnaire. Results: After the reform, students' online course examination scores were greatly improved. The "excellent" or "good" rate increased from 7.7% to 53.8%, and 96.2% of students thought they had fully achieved their teaching objectives with high satisfaction. Conclusion: The integration of the case teaching method into the pharmaceutical analysis online course improved its teaching quality; therefore, it is worth promoting and applying in the future.

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“…Removing small amounts of hazardous substances from the environment is also not easy. The processes of separation of pharmaceuticals based on the use of membranes, such as polymer inclusion membranes, not only allow the removal of even small amounts of contaminants from complex matrices with high efficiency and selectivity but also fit into the trend of the so-called “green analytical chemistry” (consumption of small amounts of chemical reagents, reduction of the use of toxic solvents, the possibility of multiple uses of membranes) [ 36 ]. Recently, PIMs have been used to remove from aqueous solutions one of the most widely utilized pharmaceuticals, ibuprofen (IBF), a non-steroidal anti-inflammatory drug, intended, inter alia, for lowering fever, pain relief and applied in the treatment of rheumatoid arthritis [ 8 ].…”

Section: Applications Of Pims For the Removal Of Selected Emerging Co...mentioning

confidence: 99%

The Application of Polymer Inclusion Membranes for the Removal of Emerging Contaminants and Synthetic Dyes from Aqueous Solutions—A Mini Review

2023

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Pollution of the environment, including water resources, is currently one of the greatest challenges due to emerging new contaminants of anthropogenic origin. Of particular concern are emerging organic pollutants such as pharmaceuticals, endocrine disruptors, and pesticides, but also other industrial pollutants, for example, synthetic dyes. The growing demand for environmentally friendly and economical methods of removing emerging contaminants and synthetic dyes from wastewater resulted in increased interest in the possibility of using techniques based on the application of polymer inclusion membranes (PIMs) for this purpose. PIM-based techniques are promising methods for eliminating emerging contaminants and synthetic dyes from aqueous solutions, including wastewater, due to high efficiency, membranes versatility, ease/low cost of preparation, and high selectivity. This review describes the latest developments related to the removal of various emerging contaminants and synthetic dyes from aqueous solutions using PIMs over the past few years, with particular emphasis on research aimed at increasing the effectiveness and selectivity of PIMs, which may contribute to wider use of these methods in the future.

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Recent developments in green membrane-based extraction techniques for pharmaceutical and biomedical analysis

Cited by 69 publications

References 241 publications

Flexible and Highly Sensitive Sandwich-Structured PDMS with Silver Nanowires and Laser-Induced Graphene for Rapid Residue Detection

Flexible and Highly Sensitive Sandwich-Structured PDMS with Silver Nanowires and Laser-Induced Graphene for Rapid Residue Detection

Application of the Case Teaching Method in a Pharmaceutical Analysis Online Course

The Application of Polymer Inclusion Membranes for the Removal of Emerging Contaminants and Synthetic Dyes from Aqueous Solutions—A Mini Review

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