Recent developments and applications of stir bar sorptive extraction

Abstract

The theoretical aspects of stir bar sorptive extraction (SBSE), as well as the recent applications of this technique in pharmaceutical, biomedical, environmental, and food analysis, and recently developed new coating procedures are reviewed. A general overview of the important factors to be evaluated in the optimization of extraction efficiency such as extraction time, matrix pH, ionic strength, effect of organic additives, temperature, agitation, pre-extraction derivatization reactions, influence of proteins, and desorption conditions are discussed. An impressive number of applications using SBSE have been published in different areas including biological, environmental, and food, showing the advantages of this technique over the classical extraction techniques (liquid-liquid extraction (LLE), Soxhlet). Although the different SBSE applications use PDMS phase as sorbent, developments of new phases are necessary for specific applications. In this review, recent SBSE developments are shown with a focus on the development of new instrumental approaches and sorbent phases.

Origins of Grape and Wine Aroma. Part 2. Chemical and Sensory Analysis

“…With SBSE, sampling occurs by placing the stir bar directly into the liquid phase for extraction, while HS-sorptive extraction (HSSE) samples from the headspace/vapor phase. The major advantage of SBSE and HSSE over SPME is that the stir bar is coated with 25 to 125 μL of sorptive phase (PDMS) compared with only ~0.5 μL of sorptive phase on a SPME fiber; the increased mass of the SBSE sorptive phase allows for a substantial increase in sensitivity (Lancas et al 2009). However, the SBSE/HSSE coatings are currently limited with respect to sorptive phase types: PDMS and PDMS/ethylene glycol co polymer are the only commercially available phases.…”

Current Developments and Future Trends in Solid-phase Microextraction Techniques for Pharmaceutical and Biomedical Analyses

“…Stir-bar sorptive extraction (SBSE) [41][42][43] ( Fig. 1B) is a new sample-preparation technique that overcomes the limited capacity of SPME fibers.…”

Possibilities of utilization of modern sample preparation methods for gas chromatographic analysis of beverages and especially beer. Part II. - Stir Bar Sorptive Extraction.

“…Další důležitou skutečností je, že kapacita PDMS fáze pro danou látku není ovlivněna přítomností vysokého obsahu vody nebo i jiných látek, protože v PDMS fázi se každá sloučenina vyznačuje svým vlastním rovnovážným stavem a nedochází tak k nežá-doucímu vytěsňování. Na druhé straně degradační části PDMS fáze obsahují typické křemíkové hmotnostní fragmenty, které se objeví v chromatogramu při použití hmotnostního detektoru [3,4].…”

“…Tento rozdělující koeficient velmi dobře koreluje s rozdělovacím koeficientem oktanolvoda (K o/w ). I když to není úplně přesné, tak hodnota rozdělovacího koeficientu oktanol-voda poskytuje velmi dobrou představu, jestli vů-bec sloučenina bude a pokud ano, tak jak dobře, extrahována pomocí metody SBSE [3,5].…”

“…Partition is controlled by the physicochemical properties of the solute, the sample matrix and the extraction phase. [2,3] Solid-phase microextraction (SPME) and stir bar sorptive extraction (SBSE) represent typical examples of these procedures. These methods combine extraction and concentration of the analytes of interest in a single step, thereby the time necessary to prepare the samples is reduced.…”