Recent development on computer aided tissue engineering — a review

Sun, Wei; Lal, Pallavi

doi:10.1016/s0169-2607(01)00116-x

Cited by 328 publications

(164 citation statements)

References 119 publications

Supporting

Mentioning

162

Contrasting

Unclassified

Order By: Relevance

“…When combined with patient XCT data, surgeons can design and produce mechanically tuneable and highly customised tissue scaffolds for direct implantation into patients. Three reviews were produced during this time that identified this technique as a viable method for production of scaffolds, as well as of prostheses and tissue models [29][30][31]. In 2003, Hollander et al [32] performed preliminary studies using XCT with SLM for the purpose of directly replacing bone using TiAl6V4 implants.…”

Section: History 1995-2005mentioning

confidence: 99%

X-ray computed tomography and additive manufacturing in medicine: a review

Thompson

McNally

Maskery

et al. 2017

Int. J. Metrol. Qual. Eng.

View full text Add to dashboard Cite

Abstract. The use of X-ray computed tomography (XCT) with additive manufacture (AM) within a medical context is examined in this review. The seven AM process families and various XCT scanning techniques are explained in brief, and the use of these technologies together is detailed over time. The transition of these technologies from a simple method of medical modelling to a robust method of customised implant manufacture is described, and the state-of-the-art for XCT and AM is examined in detail. XCT and AM are identified as having the potential to improve gold standards in both modelling and implant production, and in the conclusions of this review, primary barriers to the increased adoption of AM and XCT technologies are identified in reference to the main applications of XCT and AM technologies. The primary prohibitive factors generally relate to the cost of production across all of the examined applications, as well as the need for further clinical trials in surgical guidance and applications involving implantation.

show abstract

Section: History 1995-2005mentioning

confidence: 99%

X-ray computed tomography and additive manufacturing in medicine: a review

Thompson

McNally

Maskery

et al. 2017

Int. J. Metrol. Qual. Eng.

View full text Add to dashboard Cite

show abstract

“…Figure 1 with an overview in Figure 2. Details of the applications and developments were reported in [7][8][9], respectively.…”

Section: Introductionmentioning

confidence: 99%

Computational Approaches in Tissue Engineering

Sah¹,

Sadanand²,

Pramanik³

2011

IJCA

View full text Add to dashboard Cite

Scaffolds designed with intricate and controlled interior architecture represent a challenging problem for tissue engineering. Various scaffold-fabricating techniques allow the creation of complex micro-structure but with irregular pore characteristics, resulting in inappropriate & asymmetrical structures not suitable for tissue engineering applications. Computer-Aided Tissue Engineering (CATE) integrates advanced technologies from Biology, Information Science and Engineering for Tissue Engineering applications. In particulars, computer-aided design (CAD), medical image processing, computer-aided manufacturing (CAM), and solid freeform fabrication (SFF) are employed for simulation, design and manufacturing of tissue scaffolds with controlled and regular pore architecture. CATE application to the design and fabrication of scaffolds can guide to improve the biomimetic and biological features of the scaffolds. This paper aims to understand the principles behind various computer aided approaches being utilized for tissue engineering applications particularly cell-scaffold implant modeling, designing and manufacturing.

show abstract

“…This model system was chosen in an attempt to construct more complex three-dimensional tissue blocks by the combination of computer programmed deposition of cells or cell aggregates into macroscopically defined shapes. Moreover, this process known as computer-aided tissue engineering (CATE) [14] is based on the observation that cells have a biologically-programmed capacity for selfassembly and will differentiate during a short maturation process if provided a suitable environment, exemplified by the behavior of embryonic tissue explants [15]. We report here the fabrication of tubular cell structures that exhibit form and function.…”

Section: Introductionmentioning

confidence: 99%

Layer-by-layer printing of cells and its application to tissue engineering

Kesari¹,

Xu²,

Boland³

2004

MRS Proc.

View full text Add to dashboard Cite

Tissues and organs exhibit distinct shapes and functions nurtured by vascular connectivity.In order to mimic and examine these intricate structure-function relationships, it is necessary to develop efficient strategies for assembling tissue-like constructs.Many of the top-down fabrication techniques used to build microelectromechanical systems, including photolithography, are attractive due to the similar feature sizes, but are not suitable for delicate biological systems or aqueous environments. A layer-by layer approach has been proposed by us to pattern functional cell structures in three dimensions. Freeform cell structures are created by the inkjet method, in which cells are entrapped within hydrogels and crosslinked on demand. The cells are viable, functional and show potential for cell maturation as exemplified by the diversion of hematopoietic stem cells into multiple cell types. These results show promise for many tissue engineering applications.

show abstract

Recent development on computer aided tissue engineering — a review

Cited by 328 publications

References 119 publications

X-ray computed tomography and additive manufacturing in medicine: a review

X-ray computed tomography and additive manufacturing in medicine: a review

Computational Approaches in Tissue Engineering

Layer-by-layer printing of cells and its application to tissue engineering

Contact Info

Product

Resources

About