Recent advances in the vaccine development for the prophylaxis of SARS Covid-19

Kumar, Vipul; Kumar, S. Suresh; Sharma, Prabodh Chander

doi:10.1016/j.intimp.2022.109175

Cited by 6 publications

(4 citation statements)

References 85 publications

(79 reference statements)

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“…In fact, while in the early pandemic the phenomenon of recombination was relatively rare being the antigenic drift prevalent, 43 in the post-Omicron era recombination events have increased significantly, becoming an important mechanism of viral evolution capable of improve the virus ability to escape convalescent or postvaccination immunity. 44 Concerns arose in mid-2022 regarding the Centaurus variant (BA.2.75), which caused a temporary increase in infections (Figure 1).…”

Section: Genomic Composition and Molecular Evolution Of Sars-cov-2mentioning

confidence: 99%

“…By spring 2020, vaccination studies were already in progress. Surprisingly, within less than 12 months, the European Medicines Agency granted the first conditional authorization for a COVID‐19 vaccine in December 2020 44 . Just a month later, in January 2021, another COVID‐19 vaccine received a second recommendation 45 .…”

Section: Sars‐cov‐2 Vaccines Development: a Race Against Timementioning

confidence: 99%

“…Therefore, the virus prevailing evolutionary mechanisms changed in the last times. In fact, while in the early pandemic the phenomenon of recombination was relatively rare being the antigenic drift prevalent, 43 in the post‐Omicron era recombination events have increased significantly, becoming an important mechanism of viral evolution capable of improve the virus ability to escape convalescent or postvaccination immunity 44 …”

Section: Genomic Composition and Molecular Evolution Of Sars‐cov‐2mentioning

confidence: 99%

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Epidemic history and evolution of an emerging threat of international concern, the severe acute respiratory syndrome coronavirus 2

Giovanetti,

Branda,

Cella

et al. 2023

Journal of Medical Virology

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This comprehensive review focuses on the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and its impact as the cause of the COVID‐19 pandemic. Its objective is to provide a cohesive overview of the epidemic history and evolutionary aspects of the virus, with a particular emphasis on its emergence, global spread, and implications for public health. The review delves into the timelines and key milestones of SARS‐CoV‐2's epidemiological progression, shedding light on the challenges encountered during early containment efforts and subsequent waves of transmission. Understanding the evolutionary dynamics of the virus is crucial in monitoring its potential for adaptation and future outbreaks. Genetic characterization of SARS‐CoV‐2 is discussed, with a focus on the emergence of new variants and their implications for transmissibility, severity, and immune evasion. The review highlights the important role of genomic surveillance in tracking viral mutations linked to establishing public health interventions. By analyzing the origins, global spread, and genetic evolution of SARS‐CoV‐2, valuable insights can be gained for the development of effective control measures, improvement of pandemic preparedness, and addressing future emerging infectious diseases of international concern.

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Section: Genomic Composition and Molecular Evolution Of Sars-cov-2mentioning

confidence: 99%

Section: Sars‐cov‐2 Vaccines Development: a Race Against Timementioning

confidence: 99%

Section: Genomic Composition and Molecular Evolution Of Sars‐cov‐2mentioning

confidence: 99%

See 1 more Smart Citation

Epidemic history and evolution of an emerging threat of international concern, the severe acute respiratory syndrome coronavirus 2

Giovanetti,

Branda,

Cella

et al. 2023

Journal of Medical Virology

View full text Add to dashboard Cite

show abstract

“…Soon after, on 11 March 2020, it was declared a pandemic [1] . Since then, researchers in all parts of the world have launched intensive efforts to understand the mechanisms of its spread [2] , COVID-19 detection with medical images and biomarkers [3] , [4] , develop and study vaccines against the novel coronavirus [5] , [6] , enforcing safety measures [7] , and analyze the impact of the pandemic [8] – [16] as well as counter-measures taken by governments [17] , [18] , on society.…”

Section: Introductionmentioning

confidence: 99%