Recent Advances in Muscle Research

Sanger, Jean M.; Sanger, Joseph W.

doi:10.1002/ar.22986

Cited by 10 publications

(6 citation statements)

References 40 publications

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“…The motilin receptor does not appear to have constitutive activity [897]. Although not proven, the existence of biased agonism at the receptor has been suggested [1402,1462,1860]. A truncated 5-transmembrane structure has been identified but this is without activity when transfected into a host cell [588].…”

Section: Nomenclature Motilin Receptor Hgnc Uniprot Mlnr O43193mentioning

confidence: 99%

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors

Alexander

Christopoulos

Davenport

et al. 2019

British J Pharmacology

625

621

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The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (http://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14748. G protein‐coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

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Section: Nomenclature Motilin Receptor Hgnc Uniprot Mlnr O43193mentioning

confidence: 99%

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors

Alexander

Christopoulos

Davenport

et al. 2019

British J Pharmacology

625

621

View full text Add to dashboard Cite

show abstract

“…Where studied the motilin receptor does not appear to have constitutive activity [962]. Although not proven, the existence of biased agonism at the receptor has been suggested [1531,1597,2052]. A truncated 5-transmembrane structure has been identified but this is without activity when transfected into a host cell [5].…”

Section: Further Reading On Motilin Receptormentioning

confidence: 99%

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

Alexander

Christopoulos

Davenport

et al. 2021

British J Pharmacology

376

274

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The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15538. G protein‐coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

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“…Lasty (promise; we could go on forever), we must note the comprehensive 2014 special issue of our journal Guest Edited by Jean and Joseph Sanger on “Recent Advances in Muscle Research” (Sanger and Sanger, ; Albertine and Jensen, ). That collection of cutting‐edge science was indeed the “flip side” to this current special issue.…”

mentioning

confidence: 99%