Recent advances in ion‐sensitive field‐effect transistors for biosensing applications

Ma, Xiaohao; Peng, Ruiheng; Mao, Wei; Lin, Yuanjing; Yu, Hao

doi:10.1002/elsa.202100163

Cited by 24 publications

(11 citation statements)

References 142 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, microfabrication techniques can be used to create microarrays of FET sensors on flexible substrates, enabling the creation of flexible, lightweight, and comfortable wearable sensors that can be integrated into clothing or attached onto skin. There are generally two types of FETs-based biosensors: organic field-effective transistor (OFET) and OECT. − These two transistor-based biosensors have a similar configuration, which comprises three electrodes (i.e., source, drain, and gate electrode), a semiconducting channel layer, and a gate dielectric layer. The difference between OFET and OECT is the dielectric layer; the former one usually uses a dielectric material such as metal oxide or polymer, while the later one adopts a liquid electrolyte.…”

Section: Wearable Devices Based On Pctsmentioning

confidence: 99%

Porous Conductive Textiles for Wearable Electronics

Ding,

Jiang,

et al. 2024

Chem. Rev.

View full text Add to dashboard Cite

Over the years, researchers have made significant strides in the development of novel flexible/stretchable and conductive materials, enabling the creation of cutting-edge electronic devices for wearable applications. Among these, porous conductive textiles (PCTs) have emerged as an ideal material platform for wearable electronics, owing to their light weight, flexibility, permeability, and wearing comfort. This Review aims to present a comprehensive overview of the progress and state of the art of utilizing PCTs for the design and fabrication of a wide variety of wearable electronic devices and their integrated wearable systems. To begin with, we elucidate how PCTs revolutionize the form factors of wearable electronics. We then discuss the preparation strategies of PCTs, in terms of the raw materials, fabrication processes, and key properties. Afterward, we provide detailed illustrations of how PCTs are used as basic building blocks to design and fabricate a wide variety of intrinsically flexible or stretchable devices, including sensors, actuators, therapeutic devices, energy-harvesting and storage devices, and displays. We further describe the techniques and strategies for wearable electronic systems either by hybridizing conventional off-the-shelf rigid electronic components with PCTs or by integrating multiple fibrous devices made of PCTs. Subsequently, we highlight some important wearable application scenarios in healthcare, sports and training, converging technologies, and professional specialists. At the end of the Review, we discuss the challenges and perspectives on future research directions and give overall conclusions. As the demand for more personalized and interconnected devices continues to grow, PCT-based wearables hold immense potential to redefine the landscape of wearable technology and reshape the way we live, work, and play.

show abstract

Section: Wearable Devices Based On Pctsmentioning

confidence: 99%

Porous Conductive Textiles for Wearable Electronics

Ding,

Jiang,

et al. 2024

Chem. Rev.

View full text Add to dashboard Cite

show abstract

“…Various research has also shown that the functionalization of the biomolecules at the edges of the channel surface leads to a greater change in device conductivity and sensitivity [ 14 , 16 ]. In other types of FETs, such as ISFETs and dielectrically modulated field effect transistors (DMFETs), the sensitivity hinges on the transconductance ( dI D /dV EG ) factor, which depends on the dielectric constant of the specific biomolecule [ 38 , 39 , 40 ]. Ohno et al thus demonstrated linear changes in transconductance of ISFET with adsorption of protein molecules (bovine serum albumin) at low concentrations and saturation at higher concentrations [ 38 ]; Im et al showed binding of biomolecules in DMFET that alters the dielectric constant at the gate and causes large changes in threshold voltage, which can alter the transconductance.…”

Section: Working Principle Of the Field Effect Transistor As A Biosensormentioning

confidence: 99%

Advancement and Challenges of Biosensing Using Field Effect Transistors

Thriveni

Ghosh

2022

Biosensors

View full text Add to dashboard Cite

Field-effect transistors (FETs) have become eminent electronic devices for biosensing applications owing to their high sensitivity, faster response and availability of advanced fabrication techniques for their production. The device physics of this sensor is now well understood due to the emergence of several numerical modelling and simulation papers over the years. The pace of advancement along with the knowhow of theoretical concepts proved to be highly effective in detecting deadly pathogens, especially the SARS-CoV-2 spike protein of the coronavirus with the onset of the (coronavirus disease of 2019) COVID-19 pandemic. However, the advancement in the sensing system is also accompanied by various hurdles that degrade the performance. In this review, we have explored all these challenges and how these are tackled with innovative approaches, techniques and device modifications that have also raised the detection sensitivity and specificity. The functional materials of the device are also structurally modified towards improving the surface area and minimizing power dissipation for developing miniaturized microarrays applicable in ultra large scale integration (ULSI) technology. Several theoretical models and simulations have also been carried out in this domain which have given a deeper insight on the electron transport mechanism in these devices and provided the direction for optimizing performance.

show abstract

“…Sensors play a crucial role in converting targeted analytes into measurable electric signals, making them a vital tool in medical care and health monitoring. [1][2][3][4][5][6][7][8] The rapid development of a large library of functionalized sensors has enabled the widespread utilization of wearable sensors over the past few decades. [9][10][11][12][13] In addition, wireless transmission technologies have evolved to achieve high-speed data transfer.…”

Section: Introductionmentioning

confidence: 99%