Recent advances in bioapplications of C-dots

Zhao, Andong; Chen, Zhaowei; Zhao, Chuangqi; Gao, Nan; Ren, Jinsong; Qu, Xiaogang

doi:10.1016/j.carbon.2014.12.045

Cited by 337 publications

(172 citation statements)

References 145 publications

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“…In this current review, without pretending to being exhaustive, we for the first time provide a broad vision of characterization and analytical separation techniques for Cdots by means of 190 references published in 2004-2017, leaving aside the synthesis and applications of C-dots which have been comprehensively reviewed by a set of thorough reviews [52,[116][117][118]. In addition, some of the merits and drawbacks of the given separation and analytical techniques for C-dots are also highlighted.…”

Section: Introductionmentioning

confidence: 99%

Characterization and Analytical Separation of Fluorescent Carbon Nanodots

Gong

Liu

et al. 2017

Journal of Nanomaterials

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Carbon nanodots (C-dots) are recently discovered fluorescent carbon nanoparticles with typical sizes of <10 nm. The C-dots have been reported to have excellent photophysical and chemical characteristics. In recent years, the advances in the development and improvement in C-dots synthesis, characterization, and applications are burgeoning. In this review, we introduce the most commonly used techniques for the characterization of C-dots. The characterization techniques for C-dots are briefly classified, described, and illustrated with applied examples. In addition, the analytical separation methods for C-dots (including electrophoresis, chromatography, density gradient centrifugation, differential centrifugation, solvent extraction, and dialysis) are included and discussed according to their analytical characteristics. The review concludes with an outlook towards the future developments in the characterization and the analytical separation of C-dots. The comprehensive overview of the characterization and the analytical separation techniques will safeguard people to use each technique more wisely.

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Section: Introductionmentioning

confidence: 99%

Characterization and Analytical Separation of Fluorescent Carbon Nanodots

Gong

Liu

et al. 2017

Journal of Nanomaterials

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“…Generally, CDs can be synthesized by either "top-down" or "bottom-up" approaches [8]. The first category involves breaking larger graphitic materials into small CDs, and methods include use of arc-discharged soot [9], laser ablation of carbon targets [10], electrochemical shocking of carbon nanotubes or electrochemical exfoliation of graphite [11,12], and chemical oxidation [13].…”

Section: Introductionmentioning

confidence: 99%

Green synthesis of fluorescent carbon dots from carrot juice for in vitro cellular imaging

Liu¹,

Liu²,

Park³

et al. 2017

Carbon letters

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We report the use of carrot, a new and inexpensive biomaterial source, for preparing high quality carbon dots (CDs) instead of semi-conductive quantum dots for bioimaging application. The as-derived CDs possessing down and up-conversion photoluminescence features were obtained from carrot juice by commonly used hydrothermal treatment. The corresponding physiochemical and optical properties were investigated by electron microscopy, fluorescent spectrometry, and other spectroscopic methods. The surfaces of obtained CDs were highly covered with hydroxyl groups and nitrogen groups without further modification. The quantum yield of as-obtained CDs was as high as 5.16%. The cell viability of HaCaT cells against a purified CD aqueous solution was higher than 85% even at higher concentration (700 μg mL −1 ) after 24 h incubation. Finally, CD cultured cells exhibited distinguished blue, green, and red colors, respectively, during in vitro imaging when excited by three wavelength lasers under a confocal microscope. Offering excellent optical properties, biocompatibility, low cytotoxicity, and good cellular imaging capability, the carrot juice derived CDs are a promising candidate for biomedical applications.

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“…These properties have led to a series of potential applications as in light emitting diodes [2,3], solar cells [4,5], sensing [6], catalysis [7], integration in photovoltaic devices etc. [8] and more importantly to a possible breakthrough in biosensing, bioimaging [9][10][11][12][13] and medical diagnosis [14].…”

Section: Introductionmentioning

confidence: 99%

Successful entrapment of carbon dots within flexible free-standing transparent mesoporous organic-inorganic silica hybrid films for photonic applications

Vassilakopoulou

Georgakilas

Vainos

et al. 2017

Journal of Physics and Chemistry of Solids

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The effective entrapment of Carbon dots (CDs) into a polymer-silica hybrid matrix, formed as free standing transparent flexible films, is presented. CDs of 3 nm mean size with strong photoluminescence are embedded into a silica matrix during the sol-gel procedure, using tetraethylorthosilicate and F127 triblock copolymer as the structure directing agent under acidic conditions. The final hybrid nanostructure forms free standing transparent films that show high flexibility and long term stable CDs luminescence indicating the protective character of the hybrid matrix. It is crucial that the photoluminescence of the hybrid's CDs is not seriously affected after thermal treatment at 550 0 C for 30min. Moreover, the herein reported hybrid is demonstrated to be suitable for the fabrication of advanced photonic structures using soft lithography process due to its low shrinkage and distortion upon drying.

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Recent advances in bioapplications of C-dots

Cited by 337 publications

References 145 publications

Characterization and Analytical Separation of Fluorescent Carbon Nanodots

Characterization and Analytical Separation of Fluorescent Carbon Nanodots

Green synthesis of fluorescent carbon dots from carrot juice for in vitro cellular imaging

Successful entrapment of carbon dots within flexible free-standing transparent mesoporous organic-inorganic silica hybrid films for photonic applications

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