Reassessing the need for ventilation during CPR

Gastric insufflation during cardiopulmonary resuscitation: A study in human cadavers

“…While ventilation is critical for maintaining tissue oxygenation and CO2 elimination, during cardiac arrest, the metabolic demand is decreased due to a low cardiac output and peripheral perfusion. Even if ventilation is necessary for prolonged resuscitation (5), excessive ventilation can have a detrimental physiological effect and lead to adverse patient outcomes. Ventilating with excessive pressure, volume, or rates can also result in gastric insufflation and increased intrathoracic pressure, leading to decreased venous return and cardiac output (6,7).…”

Gastric insufflation during cardiopulmonary resuscitation: A study in human cadavers

“…While ventilation is critical for maintaining tissue oxygenation and CO2 elimination, during cardiac arrest, the metabolic demand is decreased due to a low cardiac output and peripheral perfusion. Even if ventilation is necessary for prolonged resuscitation (5), excessive ventilation can have a detrimental physiological effect and lead to adverse patient outcomes. Ventilating with excessive pressure, volume, or rates can also result in gastric insufflation and increased intrathoracic pressure, leading to decreased venous return and cardiac output (6,7).…”

Cardiopulmonary cerebral resuscitation in small animals – a clinical practice review (Part 1)

“…This variation arose because cardiac dysrhythmias secondary to coronary artery disease are common causes of CPA in people, 12 and early defibrillation is associated with the best survival rates 13,14 . In addition, there is evidence that immediate ventilation may not be necessary in CPCR 15,16 . For example, arterial pH, PCO 2 , and O 2 saturation can be maintained by external chest compression without ventilation for at least 4 min in a canine ventricular fibrillation model 15,17 .…”

Impact of Different Ventilation Strategies on Gas Exchanges and Circulation During Prolonged Mechanical Cardio-Pulmonary Resuscitation in a Porcine Model

“…Both the latest ERC and ILCOR guidelines called for 100% FiO 2 use during CPR (1,2). Ventilation strategies may impact gas exchanges and circulation differently (6), especially when CPR with mechanical chest compression is prolonged (7). Therefore, practices in the field differ according to the teams with different underlying concepts (8).…”

Gastric insufflation during cardiopulmonary resuscitation: A study in human cadavers

“…While ventilation is critical for maintaining tissue oxygenation and CO2 elimination, during cardiac arrest, the metabolic demand is decreased due to a low cardiac output and peripheral perfusion. Even if ventilation is necessary for prolonged resuscitation (5), excessive ventilation can have a detrimental physiological effect and lead to adverse patient outcomes. Ventilating with excessive pressure, volume, or rates can also result in gastric insufflation and increased intrathoracic pressure, leading to decreased venous return and cardiac output (6,7).…”

Cardiopulmonary cerebral resuscitation in small animals – a clinical practice review (Part 1)

“…This variation arose because cardiac dysrhythmias secondary to coronary artery disease are common causes of CPA in people, 12 and early defibrillation is associated with the best survival rates 13,14 . In addition, there is evidence that immediate ventilation may not be necessary in CPCR 15,16 . For example, arterial pH, PCO 2 , and O 2 saturation can be maintained by external chest compression without ventilation for at least 4 min in a canine ventricular fibrillation model 15,17 .…”

Impact of Different Ventilation Strategies on Gas Exchanges and Circulation During Prolonged Mechanical Cardio-Pulmonary Resuscitation in a Porcine Model

“…Both the latest ERC and ILCOR guidelines called for 100% FiO 2 use during CPR (1,2). Ventilation strategies may impact gas exchanges and circulation differently (6), especially when CPR with mechanical chest compression is prolonged (7). Therefore, practices in the field differ according to the teams with different underlying concepts (8).…”

Gastric insufflation during cardiopulmonary resuscitation: A study in human cadavers

“…While ventilation is critical for maintaining tissue oxygenation and CO2 elimination, during cardiac arrest, the metabolic demand is decreased due to a low cardiac output and peripheral perfusion. Even if ventilation is necessary for prolonged resuscitation (5), excessive ventilation can have a detrimental physiological effect and lead to adverse patient outcomes. Ventilating with excessive pressure, volume, or rates can also result in gastric insufflation and increased intrathoracic pressure, leading to decreased venous return and cardiac output (6,7).…”

Cardiopulmonary cerebral resuscitation in small animals – a clinical practice review (Part 1)

“…This variation arose because cardiac dysrhythmias secondary to coronary artery disease are common causes of CPA in people, 12 and early defibrillation is associated with the best survival rates 13,14 . In addition, there is evidence that immediate ventilation may not be necessary in CPCR 15,16 . For example, arterial pH, PCO 2 , and O 2 saturation can be maintained by external chest compression without ventilation for at least 4 min in a canine ventricular fibrillation model 15,17 .…”

Impact of Different Ventilation Strategies on Gas Exchanges and Circulation During Prolonged Mechanical Cardio-Pulmonary Resuscitation in a Porcine Model

“…Both the latest ERC and ILCOR guidelines called for 100% FiO 2 use during CPR (1,2). Ventilation strategies may impact gas exchanges and circulation differently (6), especially when CPR with mechanical chest compression is prolonged (7). Therefore, practices in the field differ according to the teams with different underlying concepts (8).…”