Reappraising basosquamous carcinoma: a summary of histologic features, diagnosis, and treatment

Intra-arterial infusion chemotherapy in the treatment of advanced basosquamous carcinoma of the nose

“…Compared with BCC and squamous cell carcinoma, BSC is an aggressive neoplasm with a higher risk of recurrence and metastases. 1 , 2 The surgical risk of incomplete excision in BSC appears to be similar to that of BCC, depending on the site, size, and whether primitive or recurrent. 1 , 2 Published recurrent rates were 12% to 51% for surgical excision and 4% for Mohs micrographic surgery.…”

“… 1 , 2 The surgical risk of incomplete excision in BSC appears to be similar to that of BCC, depending on the site, size, and whether primitive or recurrent. 1 , 2 Published recurrent rates were 12% to 51% for surgical excision and 4% for Mohs micrographic surgery. 1 , 2 The incidence of metastasis was at least 5%.…”

“…Basosquamous carcinoma (BSC) is a rare, aggressive tumor defined as a subtype of basal cell carcinoma (BCC), characterized by an aggressive subclinical spread with higher rates of recurrence and metastatic potential. 1 , 2 There are no clear guidelines concerning BSC management. 1 , 2 Treatments such as wide local excision, Mohs micrographic surgery, radiotherapy, and palliative chemotherapy have been reported.…”

“… 1 , 2 There are no clear guidelines concerning BSC management. 1 , 2 Treatments such as wide local excision, Mohs micrographic surgery, radiotherapy, and palliative chemotherapy have been reported. 1 , 2 The present report describes the complete regression of an extensive and locally destructive BSC involving the nasal septum and sinuses in a patient after a 4-month regimen of intra-arterial (IA) infusion of low-dose cisplatin.…”

Metatypical basal cell carcinoma: from the primary tumour to a generalized metastatic process – description of diagnostics and combination therapy of an extremely rare skin cancer

“…Clinical findings concerning the use of chemotherapy are rarely reported. Systemic chemotherapy usually uses cisplatin, doxorubicin, 5-fluorouracil [14,18].…”