Reappraisal of cerebellopontine angle medulloblastomas: Report of a fatal case and lessons learned

Goudihalli, Sachin Ranganatha; Pathak, Ashis; Brar, Rahat; Mundi, Irneet

doi:10.1016/j.inat.2017.12.001

Cited by 8 publications

(27 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…So far, there is no clear-cut consensus as to whether the CPA medulloblastomas are more aggressive compared with their vermian counterpart. 6,14 We believe this may indicate a probable higher malignant potential of CPA medulloblastomas in comparison to their vermian counterpart. Surgery via the retromastoid route, followed by radiotherapy, remains the main treatment modality to manage these cases.…”

Section: Discussionmentioning

confidence: 88%

“…There have been only 10 reported cases of extra-axial medulloblastoma in the adult literature. 6 The table describes CPA medulloblastomas described in the past, presentation, management, and outcome compared to the present case (►Table 1); however, they are likely to be underreported owing to publication bias. This tumor is nearly twice as common in men.…”

Section: Discussionmentioning

confidence: 99%

“…The tumors most often occur among patients in their late 20s and early 30s. 6 It has been observed that the two most common sites for extra-axial locations are the tentorial and CPA regions. 3,[6][7][8][9][10][11][12] Most commonly, they manifest as heterogeneously enhancing lesions upon contrast administration.…”

Section: Discussionmentioning

confidence: 99%

“…[2][3][4][5] Extra-axial CPA medulloblastoma is extremely rare and only 10 adult cases have been reported in world literature. 6…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Extra-axial Cerebellopontine Angle Adult Medulloblastoma: An Unusual Presentation at an Unusual Site

Ratha

Karmarkar

Deopujari

2019

IJNS

View full text Add to dashboard Cite

Medulloblastoma is a rare adult primary brain tumor and its presence in the cerebellopontine angle (CPA) constitutes an even rarer site for origin. There are only 40 reported cases of CPA medulloblastoma in the literature, with most being intra-axial and occurring in the pediatric population. Extra-axial CPA medulloblastoma in adults are extremely rare and only 10 adult cases have been reported in world literature.We report a rare case of primary extra-axial CPA medulloblastoma occurring in an adult. We review the literature for such an unusual presentation of medulloblastoma in adults and discuss its appropriate clinico-radiological features along with its possible pathogenesis and surgical management.With increasing reporting of such tumors, CPA region, medulloblastoma should be considered a differential diagnosis of intra-axial or extra-axial CPA tumor, as their further management and prognosis differ significantly. Adjuvant radiotherapy and combined chemotherapy regimen should be added to the postoperative management.

show abstract

Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…[2][3][4][5] Extra-axial CPA medulloblastoma is extremely rare and only 10 adult cases have been reported in world literature. 6…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Extra-axial Cerebellopontine Angle Adult Medulloblastoma: An Unusual Presentation at an Unusual Site

Ratha

Karmarkar

Deopujari

2019

IJNS

View full text Add to dashboard Cite

show abstract

“…Incidence in adult population is less than 1 %. [1] Medulloblastoma in adult usually between 20 and 40 years old, which is lateral hemispheric and not midline vermian. [2] Survival rate in adult is 67% lower than children is 72%.…”

Section: Introductionmentioning

confidence: 99%

Medulloblastoma: Intraventricular Recurrences

Setiawan

Wijaya

Dharmajaya

2019

AANHS-J

View full text Add to dashboard Cite

Medulloblastoma is the most common malignant pediatric brain tumor. Incidence in adult population is less than 1 %. Medulloblastoma in adult usually between 20 and 40 years old, which is lateral hemispheric and not midline vermian. Survival rate in adult is 67% lower than adolescents is 69% and children is 72%. Location of recurrences most commonly presents at posterior fossa, spinal, supratentorial, and bone metastases. Recurrences of medulloblastoma in supratentorial ventricular is uncommon. The outcome for patients with recurrent medulloblastoma has historically been poor. 37 years old male who presented with severe headache gradually. Patient has history of headache 2 months ago and gait ataxia 1,5 months ago. Patient had surgery 2 years ago with result of hystopathology medulloblastoma. He had irradiation completely 22 months ago. Physical examination showed GCS 15 with gait ataxia. Head CT scan show multiple isodense lesion intraventricular. Before patient had surgery, Head CT scan showed hiperdense lesion at cerebellopontine angle. Seeding medulloblastoma to intraventricular is recurrences which have poor prognosis. Patient had poor condition in few days. Patient died before got reriradiation

show abstract

Medulloblastoma at the cerebello-pontine angle resembling vestibular schwannoma: A case report and review of the literature

Aqel

Salman²,

Aldarawish³

et al. 2022

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

Reappraisal of cerebellopontine angle medulloblastomas: Report of a fatal case and lessons learned

Cited by 8 publications

References 14 publications

Extra-axial Cerebellopontine Angle Adult Medulloblastoma: An Unusual Presentation at an Unusual Site

Extra-axial Cerebellopontine Angle Adult Medulloblastoma: An Unusual Presentation at an Unusual Site

Medulloblastoma: Intraventricular Recurrences

Medulloblastoma at the cerebello-pontine angle resembling vestibular schwannoma: A case report and review of the literature

Contact Info

Product

Resources

About