Real frequency of ordinary and atypical sub-trochanteric and diaphyseal fractures in France based on X-rays and medical file analysis

Beaudouin-Bazire, Constance; Dalmas, Noémie; Bourgeois, Julie; Babinet, Antoine; Anract, Philippe; Chantelot, Christophe; Farizon, Frédéric; Chopin, Florence; Briot, Karine; Roux, Christian; Cortet, Bernard; Thomas, Thierry

doi:10.1016/j.jbspin.2012.07.012

Cited by 22 publications

(16 citation statements)

References 31 publications

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“…The incidence of the patients taking a BP with AFFs was varying from 41.6% to 97%9171819). Our study showed about 60% of the patients had taken BP in both groups.…”

Section: Discussionmentioning

confidence: 61%

Lateral Femoral Bowing and the Location of Atypical Femoral Fractures

et al. 2017

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PurposeAtypical femoral fractures (AFFs) occur in two distinct part, subtrochanter and diaphysis. The aim of this study was to investigate the relationship between the lateral femoral bowing angle and the location of AFF.Materials and MethodsThis study included a total of 56 cases in 45 patients who underwent surgical treatment between January 2010 and December 2015. For the diaphyseal and subtrochanteric AFFs, we evaluated the relationship between the anatomic location and lateral femoral bowing angle. Lateral femoral bowing angle was measured by two orthopaedic surgeons and average value of two calibrators was used in statistic analysis. Other variables like age, height, weight, body mass index and bone mineral density were also evaluated. We also calculated the cutoff value for the location of the fractures from the raw data.ResultsThe average lateral femoral bowing angle was 10.10°±3.79° (3°-19°) in diaphyseal group and 3.33°±2.45° (1.5°-11°) in subtrochanter group. Lateral femoral bowing angle was statistically significant in logistic regression analysis. According to the receiver operating characteristic curve, cutoff value for the location of the fracture was 5.25°. In other words, the femoral diaphyseal fractures are more frequent if the lateral femoral bowing angle is greater than 5.25°.ConclusionThe lateral femoral bowing angle is associated with the location of the AFFs and the cutoff value of lateral femoral bowing angle was 5.25°.

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“…The incidence of the patients taking a BP with AFFs was varying from 41.6% to 97%9171819). Our study showed about 60% of the patients had taken BP in both groups.…”

Section: Discussionmentioning

confidence: 61%

Lateral Femoral Bowing and the Location of Atypical Femoral Fractures

et al. 2017

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“…One study in Norway which included periprosthetic fractures showed a mean incidence of 9.8 per 100,000 person-years (95% CI 5.2-14.5) amongst women aged ≥65 years (23). Using the first ASBMR definition, the prevalence of AFFs accounted for only 0.2-0.8% of total hip fractures and 3.5-30.3% of subtrochanteric and femoral shaft fractures (13,(17)(18)(19)(20). Similarly, three studies using the revised ASBMR definition reported a low prevalence of AFFs, estimated to be 0.63% of total hip fractures and 3.5-5.7% of subtrochanteric and femoral shaft fractures (22,24,25).…”

Section: The Epidemiology Of Affsmentioning

confidence: 99%

“…They were divided into two subgroups using either: (a) the first ASBMR definition (n = 10) (12)(13)(14)(15)(16)(17)(18)(19)(20)(21) or (b) the second ASBMR definition (n = 4) (22-25) ( Table 1). Seven were retrospective case-control studies, six were retrospective cohort studies and one used combined data from three prospective registries ( Table 1).…”

Section: The Epidemiology Of Affsmentioning

confidence: 99%

Epidemiology and postoperative outcomes of atypical femoral fractures in older adults: A systematic review

Khow

Shibu

et al. 2017

The Journal of nutrition, health and aging

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The benefits of bisphosphonates in reducing osteoporotic fractures still outweigh the risk of AFFs in view of its low absolute risk, when the ASBMR Task Force criteria for this type of fracture were applied. The risk of AFFs in different age groups is not well defined but tends to affect the younger patients more (aged <65 years) as compared to the older population (aged ≥65 years). Evidence supporting different types of treatment in AFFs such as intramedullary or extramedullary surgical devices and the use of teriparatide, a parathyroid hormone analogue, is not yet well established.

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“…However, once it occurs, it takes much time to heal [64,65], and the daily life activities of the patient are often impaired. Risk factors for AFF other than long-term BP use include glucocorticoid therapy [66,67], complicating connective tissue disease [67], lateral bowing of the femur [68,69], a low level of serum 25-hydroxyvitamin D [66], and female gender [70]. Glucocorticoid therapy has been reported to have an important impact on AFF [66,67], although no signiicant…”

Section: Atypical Femoral Fracturementioning

confidence: 99%

Idiopathic Osteonecrosis and Atypical Femoral Fracture in Systemic Lupus Erythematosus

Kuroda¹,

Sato²

2017

Lupus

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Osteonecrosis and osteoporosis are frequent adverse efects of glucocorticoid therapy of systemic lupus erythematosus (SLE). Idiopathic osteonecrosis (ION) of the femoral head occurs in 3-40% of patients receiving glucocorticoid, and can also develop in other bones. Higher doses of glucocorticoid and steroid pulse therapy are considered to be risk factors for ION of the femoral head. To analyze these risk factors, it seems important to detect early changes in the femoral head by magnetic resonance imaging and to monitor early clinical events atributable to steroid therapy. Prophylaxis with statins and warfarin remains debatable. The use of glucocorticoid is increase the risk of bone fractures. Bisphosphonate (BP) is used for its prevention and treatment of osteoporosis. Atypical femoral fracture (AFF) has been recently recognized as a complication associated with BP use. AFF is considered to be a form of stress fracture; localized periosteal thickening of the lateral cortex is often present at the fracture site. The thickening has been recently recognized as a complication associated with the use of antiresorptive agents such as BP and denosumab. As long-term BP/glucocorticoid use is a risk factor for beaking in patients with SLE , temporary withdrawal of BP administration should be considered.

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Real frequency of ordinary and atypical sub-trochanteric and diaphyseal fractures in France based on X-rays and medical file analysis

Cited by 22 publications

References 31 publications

Lateral Femoral Bowing and the Location of Atypical Femoral Fractures

Lateral Femoral Bowing and the Location of Atypical Femoral Fractures

Epidemiology and postoperative outcomes of atypical femoral fractures in older adults: A systematic review

Idiopathic Osteonecrosis and Atypical Femoral Fracture in Systemic Lupus Erythematosus

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