2020 DOI: 10.20944/preprints202009.0693.v1 View full text Preprint
Ammira Akil, Laila Ali, Esraa Yassin, Khalid A. Fakhro, Sujitha Jeya, Alya Al-Kurbi

Abstract: Type 1 diabetes (T1D) is an autoimmune condition where the body’s immune cells destroy their insulin-producing pancreatic beta-cells leading to dysregulated glycaemia. Individuals with T1D control their blood glucose through exogenous insulin replacement therapy, often using multiple daily injections or pumps. However, failure to accurately mimic intrinsic glucose regulation results in glucose fluctuations and long-term complications impacting key organs such as the heart, kidneys, and/or the eyes. I…

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