Reactive Psychoses

Profiles of Genetic Risks for Psychotic Disorders

“…The few available studies of DD mostly suggest, consistent with our findings, a lower risk for SZ in relatives compared with that found in relatives of patients with SZ . Regarding AP, relatives of schizophreniform probands have lower risk for SZ than relatives of patients with SZ, and similar results have been reported for “acute and transient psychotic disorders.” But our results do not support prior evidence that AP has a closer familial link to mood disorders than SZ . One prior family study of PNOS reported risk for SZ in relatives to be similar to that seen in SZ probands and rates of affective illness indistinguishable from that found in controls .…”

Reactive Psychosis

“…In Scandinavian countries, RP accounted for 13%–30% of all admissions for functional psychoses in the late 1970s (Dahl, 1987), and the lifetime risk was estimated at approximately 1% in people aged 15–55 years (Strömgren, 1974). The age of onset is to be found in early-middle adulthood with higher rates in women (Andersen and Laerum, 1980; Faergeman, 1963; McCabe, 1975; Retterstøl, 1966; Ungvari and Hantz, 1990).…”

“…Early studies conducted in Scandinavian countries indicate that RP is associated neither with a strong hereditary basis nor increased family risk for schizophrenia; the differentiation from affective disorders remains less clear (Astrup et al, 1962; Goplerud and Depue, 1978; McCabe and Strömgren, 1975; Shapiro, 1970). Similar findings were reported by studies comparing first-degree relatives of patients with schizophrenia-like emotion psychosis and family members of probands with schizophrenia (Labhardt, 1963; Rohr, 1961).…”

“…There is also evidence that depressive and neurotic traits (shyness, oversensitivity, etc.) are more likely to be described in RP than schizoid personality (Astrup et al, 1962; Chavan and Kulhara, 1988; Labhardt, 1963; McCabe, 1975; Pandurangi and Kapur, 1980; Refsum and Astrup, 1980; Retterstøl 1966).…”

“…Those people who develop RP are sensitive to life events whose characteristics and meaning are relevant to determining threats to self-esteem or self-image such as interpersonal, moral, sexual, and religious conflicts (Faergeman, 1963; McCabe, 1975; Retterstøl, 1966). However, they are hardly ever mentioned in empirical research probably because they considered as illness-related and difficult to measure by means of standard methods (Strömgren, 1989).…”