2007
DOI: 10.1038/sj.emboj.7601623 View full text |Buy / Rent full text
Has correction 2019-5-15Comment 2007-7-16Has erratum 2019-5-15
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Abstract: Autophagy is a major catabolic pathway by which eukaryotic cells degrade and recycle macromolecules and organelles. This pathway is activated under environmental stress conditions, during development and in various pathological situations. In this study, we describe the role of reactive oxygen species (ROS) as signaling molecules in starvation-induced autophagy. We show that starvation stimulates formation of ROS, specifically H 2 O 2 . These oxidative conditions are essential for autophagy, as treatment with … Show more

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