1999
DOI: 10.1016/s0099-2399(99)80134-4
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Reaction of rat connective tissue to implanted dentin tubes filled with mineral trioxide aggregate or calcium hydroxide

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Cited by 363 publications
(523 citation statements)
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“…Scientific investigations have shown that MTA can release various ions thatconduct and induct hard-tissue formation 4,17 .MTA presents some advantages,including its physical characteristics thatguarantee expansion during the attachment, which favors sealing, and the biological properties ofcalcium hydroxide 3,24 . MTA forms calcium oxide when in contact with water, which then, when in contact with tissue fluids, forms calcium hydroxide and triggers the same repair process in the tissue 11 .Some recentstudies have reported on the success of MTA as a root apical barrier, with rates ranging from 76.5% to 91% 10,20 .…”
Section: Discussionmentioning
confidence: 99%
“…Scientific investigations have shown that MTA can release various ions thatconduct and induct hard-tissue formation 4,17 .MTA presents some advantages,including its physical characteristics thatguarantee expansion during the attachment, which favors sealing, and the biological properties ofcalcium hydroxide 3,24 . MTA forms calcium oxide when in contact with water, which then, when in contact with tissue fluids, forms calcium hydroxide and triggers the same repair process in the tissue 11 .Some recentstudies have reported on the success of MTA as a root apical barrier, with rates ranging from 76.5% to 91% 10,20 .…”
Section: Discussionmentioning
confidence: 99%
“…PC and MTA contain calcium oxide, which, when mixed with water, forms calcium hydroxide, which induces an increase of pH by dissociation of calcium and hydroxide ions 6,[21][22] .…”
Section: Discussionmentioning
confidence: 99%
“…The MTA and Portland cement has similarities in their chemical composition, physical properties, biocompatibility and tissue response [5][6][7][8][9] . Therefore, the aim of this study was to evaluate the antimicrobial activity of MTA e PC against some selected cariogenic bacteria.…”
Section: Introductionmentioning
confidence: 99%
“…Sin embargo, su aparente éxito en la terapia pulpar vital ha sido cuestionado, ya que genera necrosis superficial del tejido pulpar cuando es colocado en contacto directo con este en su estado puro, gracias a su pH alcalino (pH 12), siendo cáustico para el tejido pulpar [4]. Estudios han mostrado que el hidróxi-do de calcio es muy tóxico para las células, además de presentar un efecto de disolución del tejido, lo que hace que su uso en terapias pulpares sea cuestionado [5][6][7][8].…”
Section: Introductionunclassified