Reaction of dogs' teeth to root canal filling with mineral trioxide aggregate or a glass ionomer sealer

Newly developed mineral trioxide aggregate containing polyvinyl alcohol

“…Furthermore, it was suggested that because hardened MTA continuously elutes Ca 2+ in the artificial body fluid, Ca(OH)2 is formed, and the preservation of a strongly alkaline environment leads to antibacterial activity 25) . The MTA-PVA paste exhibits the same apatite-formation ability as that reported for MTA solutions 5,6) and it might yield good medical results.…”

“…An endodontic study in dogs reported cementum deposition immediately adjacent to MTA used the retrograde filling material 4) . Holland R et al 5,6) reported that the tricalcium oxide in MTA reacts with tissue to form calcium hydroxide, resuting in hard-tissue formation. MTA showed the antibacterial activity because initially MTA has a pH of 10.2, which rises to 12.5 at 3 h after mixing 1) .…”

Histological, ultrastructural and quantitative investigations on the response of healthy human pulps to experimental capping with Mineral Trioxide Aggregate: a randomized controlled trial¶

“…It has been successfully used for retrogradefilling of root ends and to close iatrogenic perforations of roots (Lee et al 1993) and furcations . Attempts have also been made to use it as a root canal filling material in dogs (Holland et al 1999b). Dentine bridge-like hard tissue was consistently observed when MTA was used as a pulp capping agent in monkeys (Pitt Ford et al 1996), dogs (Tziafas et al 2002, Asgary et al 2006 and rats (Salako et al 2003).…”

The effects of incorporation of silver-zeolite on selected properties of mineral trioxide aggregate

“…This is an extensively described method 20,30) . MTA stimulated hard tissue deposition and it has been suggested that this important formation mechanism started with calcium ions release from MTA 31) . Similar to present study, Santos et al 20) .…”