Re: Septic arthritis due to a Savannah Monitor lizard bite: A case                     report

Tehrani, Hamid; Tejero-Trujeque, R.; Dhital, Sanjiv K.

doi:10.1177/1753193408092495

Cited by 7 publications

(4 citation statements)

References 4 publications

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“…Fry et al (2009), however, note that no compelling evidence supports the presence of pathogenic bacteria in the saliva of Varanus komodoensis, a hypothesis supported by Goldstein et al (2013) based on captive Komodo dragons. Yet, Tehrani et al (2008) and Vikrant and Verma (2014) have reported septic effects of varanid bites, and pathogenic bacteria might, therefore, be present and possibly hosted within interdenticular sulci of the crowns of wild varanids.…”

Section: Interdenticular Sulcimentioning

confidence: 99%

The distribution of dental features in non-avian theropod dinosaurs: Taxonomic potential, degree of homoplasy, and major evolutionary trends

Hendrickx

Mateus

Araújo

et al. 2019

Palaeontol Electron

150

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Section: Interdenticular Sulcimentioning

confidence: 99%

The distribution of dental features in non-avian theropod dinosaurs: Taxonomic potential, degree of homoplasy, and major evolutionary trends

Hendrickx

Mateus

Araújo

et al. 2019

Palaeontol Electron

150

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“…The activities of varanid lizard venoms have received little research attention, despite anecdotal evidence in the form of bite reports regularly describing profuse and persistent bleeding, clearly beyond the mechanical damage produced by the bite [1,51,52,53,54]. Indeed, many [13,18] are still sceptical of venom in varanids which may have deterred further investigation by other researchers.…”

Section: Introductionmentioning

confidence: 99%

Varanid Lizard Venoms Disrupt the Clotting Ability of Human Fibrinogen through Destructive Cleavage

Dobson

Zdenek

Hay

et al. 2019

Toxins

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The functional activities of Anguimorpha lizard venoms have received less attention compared to serpent lineages. Bite victims of varanid lizards often report persistent bleeding exceeding that expected for the mechanical damage of the bite. Research to date has identified the blockage of platelet aggregation as one bleeding-inducing activity, and destructive cleavage of fibrinogen as another. However, the ability of the venoms to prevent clot formation has not been directly investigated. Using a thromboelastograph (TEG5000), clot strength was measured after incubating human fibrinogen with Heloderma and Varanus lizard venoms. Clot strengths were found to be highly variable, with the most potent effects produced by incubation with Varanus venoms from the Odatria and Euprepriosaurus clades. The most fibrinogenolytically active venoms belonged to arboreal species and therefore prey escape potential is likely a strong evolutionary selection pressure. The results are also consistent with reports of profusive bleeding from bites from other notably fibrinogenolytic species, such as V. giganteus. Our results provide evidence in favour of the predatory role of venom in varanid lizards, thus shedding light on the evolution of venom in reptiles and revealing potential new sources of bioactive molecules useful as lead compounds in drug design and development.

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“…Monitor lizards, also known as biawak or goannas, belong to the genus Varanus and are related to Komodo dragons. A case of Pseudomonas aeruginosa septic arthritis after a bite from a monitor lizard was reported (210).…”

Section: Reptilesmentioning

confidence: 99%

Microbiology of Animal Bite Wound Infections

2011

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SUMMARY The microbiology of animal bite wound infections in humans is often polymicrobial, with a broad mixture of aerobic and anaerobic microorganisms. Bacteria recovered from infected bite wounds are most often reflective of the oral flora of the biting animal, which can also be influenced by the microbiome of their ingested prey and other foods. Bacteria may also originate from the victim's own skin or the physical environment at the time of injury. Our review has focused on bite wound infections in humans from dogs, cats, and a variety of other animals such as monkeys, bears, pigs, ferrets, horses, sheep, Tasmanian devils, snakes, Komodo dragons, monitor lizards, iguanas, alligators/crocodiles, rats, guinea pigs, hamsters, prairie dogs, swans, and sharks. The medical literature in this area has been made up mostly of small case series or case reports. Very few studies have been systematic and are often limited to dog or cat bite injuries. Limitations of studies include a lack of established or inconsistent criteria for an infected wound and a failure to utilize optimal techniques in pathogen isolation, especially for anaerobic organisms. There is also a lack of an understanding of the pathogenic significance of all cultured organisms. Gathering information and conducting research in a more systematic and methodical fashion through an organized research network, including zoos, veterinary practices, and rural clinics and hospitals, are needed to better define the microbiology of animal bite wound infections in humans.

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Re: Septic arthritis due to a Savannah Monitor lizard bite: A case report

Cited by 7 publications

References 4 publications

The distribution of dental features in non-avian theropod dinosaurs: Taxonomic potential, degree of homoplasy, and major evolutionary trends

The distribution of dental features in non-avian theropod dinosaurs: Taxonomic potential, degree of homoplasy, and major evolutionary trends

Varanid Lizard Venoms Disrupt the Clotting Ability of Human Fibrinogen through Destructive Cleavage

Microbiology of Animal Bite Wound Infections

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