Rate of Concurrent Otitis Media in Upper Respiratory Tract Infections With Specific Viruses

Clinical Assessment and Improved Diagnosis of Bocavirus-induced Wheezing in Children, Finland

“…The highest rate of AOM (72%) was in children with RSV-induced wheezing. Alper et al reported differences in frequencies of various respiratory viruses associated with AOM (HBoV was not included), but statistical significance was not achieved (40). We found a difference in the frequency of AOM between children with RSV-induced wheezing and those with HBoV-induced wheezing.…”

Immunohistochemical and qPCR Detection of SARS-CoV-2 in the Human Middle Ear Versus the Nasal Cavity: Case Series

“…Hence SARS-CoV-2 colonizes the ME at comparable viral loads in our preliminary findings although additional samples are required to strengthen these comparisons. Moreover, given the lower viral loads observed in the ME tissue compared to the nasal cavity, we hypothesize that ME viral entry occurs via the eustachian tube, as previously demonstrated by other viral URT infections that lead to otitis media [ 5 , 15 ]. However, circulation-mediated viral entry is also possible.…”

Panel 5: Microbiology and Immunology Panel

“…Sixty‐two percent of newly diagnosed OM episodes occurred during a respiratory infection, and 27% of respiratory infections were complicated by OM. The same group also showed that new OM was associated with the presence of virus in the nasopharynx irrespective of the presence or absence of symptomatic URI 23 . There was no significant difference between various respiratory viruses.…”

“…The same group also showed that new OM was associated with the presence of virus in the nasopharynx irrespective of the presence or absence of symptomatic URI. 23 There was no significant difference between various respiratory viruses.…”