Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2012.01.017 View full text
Tong Xie, Yan Liang, Haiping Hao, Jiye A, Lin Xie, Ping Gong, Chen Dai, Linsheng Liu, An Kang, Xiao Zheng, Guangji Wang

Abstract: This study was to develop and evaluate a practical approach of mass defect filtering (MDF), a post-acquisition data processing technique, for the rapid classification of complicated peaks into well-known chemical families based on the exact mass acquired by high resolution mass spectrometry. The full-scan LC-MS/MS data of the Ophiopogon japonicus extract was acquired using high performance liquid chromatography coupled with hybrid quadrupole-time of flight (LCMS-Q-TOF) system which features high resolution, ma…

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