Randomized comparison of postoperative use of hydrogel ocular bandage and collagen corneal shield for wound protection and patient tolerability after cataract surgery

Abstract

No author has a financial or proprietary interest in any material or method mentioned. Additional disclosures are found in the footnotes.

Intracameral phenylephrine and ketorolac injection (OMS302) for maintenance of intraoperative pupil diameter and reduction of postoperative pain in intraocular lens replacement with phacoemulsification

“…Results of a prospective study performed specifically to evaluate postoperative pain following cataract surgery reported that approximately one third of patients undergoing cataract surgery report ocular pain during the first 4 postoperative hours, with a quarter of these patients experiencing moderate to severe pain 16. The study also reported that over half of patients experienced postoperative eye symptoms, such as foreign body sensation, pruritus, and irritation, which are often interpreted as ocular findings rather than pain by ophthalmologists 17. As such, given the variable differences associated with each individual’s personal definition of pain and pain severity, the incidence of pain following cataract surgery may be higher than currently reported.…”

A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens

“…A synthetic corneal bandage has many advantages over biologically derived products in terms of reproducibility of its properties and overcoming the need to use animal derived materials or an allogeneic graft. [13][14][15] An ideal bandage contact lens should be transparent, have a high water content, have suffi cient mechanical properties for handling and be antimicrobial. This study developed poly-ε-lysine (pεK)-based Supporting Information) demonstrated a reduction as the chain length of the fatty acid increased.…”

The effect of stromal hydration on surgical outcomes for cataract patients who received a hydrogel ocular bandage

“…The recent clinical trial referenced previously by Dell and colleagues evaluated the safety and efficacy of the hydrogel bandage 12. This prospective randomized controlled clinical study of over 400 patients showed that the device was well tolerated when placed over a cataract incision.…”

“…This was a post-hoc analysis performed on a subset of data from a controlled, prospective, randomized, parallel-group multicenter study (n = 420) comparing the ReSure Adherent Ocular Bandage (Ocular Therapeutix, Inc) with the Oasis 24-hour Soft Shield ® Collagen Corneal Shield (Oasis Medical, Glendora, CA, USA) for protection and relief of pain and discomfort following cataract surgery 12. The current analysis included all the hydrogel bandage patients (n = 310) from the original study (except for six patients who received sutures), which comprised 40 patients who did not undergo stromal hydration during surgery and 270 who did receive hydration.…”

“…Detailed methods of the prospective randomized clinical trial are described by Dell et al12 Briefly, the study included adults who were scheduled for unilateral clear corneal cataract surgery with phacoemulsification and implantation of a posterior chamber intraocular lens through a ≤3.5 mm incision. The surgery was performed using a short-acting (duration of about 10–12 minutes) topical anesthetic agent (lidocaine, proparacaine, or tetracaine).…”