Raman Fingerprints of SARS-CoV-2 Omicron Subvariants: Molecular Roots of Virological Characteristics and Evolutionary Directions
Giuseppe Pezzotti,
Eriko Ohgitani,
Yuki Fujita
et al.
Abstract:The latest RNA genomic mutation of
SARS-CoV-2 virus, termed the
Omicron variant, has generated a stream of highly contagious and antibody-resistant
strains, which in turn led to classifying Omicron as a variant of
concern. We systematically collected Raman spectra from six Omicron
subvariants available in Japan (i.e., BA.1.18, BA.2, BA.4, BA.5, XE,
and BA.2.75) and applied machine-learning algorithms to decrypt their
structural characteristics at the molecular scale. Unique Raman fingerprints
of sulfur-contain… Show more
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