Ramadan fasting and chronic kidney disease: does estimated glomerular filtration rate change after and before Ramadan? Insights from a mini meta-analysis

Bragazzi, Nicola Luigi

doi:10.2147/ijnrd.s61718

Cited by 36 publications

(36 citation statements)

References 15 publications

(33 reference statements)

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“…Currently, there are no uniform and accepted guidelines or protocols that can aid clinicians in consulting CKD patients who wish to adhere to the commandment of fasting during Ramadan [20, 21]. The 2 study groups (fasting and non-fasting patients) had similar demographic and clinical characteristics, including age, sex, eGFR, BMI, hemoglobin, serum albumin, percentage of patients with diabetes and hypertension, and severity of the renal failure (Table 1).…”

Section: Discussionmentioning

confidence: 99%

Does Ramadan Fasting Affect Hydration Status and Kidney Function in CKD Patients?

et al. 2018

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Background/Aims: This study is the first of its kind to examine the impact of the Ramadan fasting on hydration status, plasma brain natriuretic peptide (BNP) levels, and kidney function in chronic kidney disease (CKD) patient. Methods: This prospective cohort study included 2 groups of patients with CKD grades 2–4: thirty-one Muslim patients who fasted the month of Ramadan (fasting group) and 26 Muslim patients who did not fast (control group). One week before the Ramadan fast, in the last week of the month of Ramadan (4 weeks), and 4 weeks after the end of the Ramadan month (8 weeks), hydration status and blood analysis of urea, creatinine and BNP levels were measured. Results: Among fasting patients, serum urea levels increased significantly (p = 0.024) during the last week of fasting and returned to basal levels at 4 weeks after the end of the Ramadan month, the estimated glomerular filtration rate did not change significantly at the end of fasting (p = 0.411), the hydration status indices and plasma BNP levels were significantly decreased after fasting (p ≤ 0.021) but returned to basal values 4 weeks thereafter. Conclusions: Patients with CKD grades 2–4 can fast throughout the month of Ramadan with no significant deterioration of renal functions and with a reasonable degree of safety.

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Section: Discussionmentioning

confidence: 99%

Does Ramadan Fasting Affect Hydration Status and Kidney Function in CKD Patients?

et al. 2018

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“…In recent meta‐analysis carried out by Bragazzi that included patients with stable CKD and not yet on dialysis, it was concluded that such patients can safely fast during Ramadan with no significant change occurring in their glomerular filtration rate as a result of fasting …”

Section: Discussionmentioning

confidence: 99%

“…In recent meta-analysis carried out by Bragazzi that included patients with stable CKD and not yet on dialysis, it was concluded that such patients can safely fast during Ramadan with no significant change occurring in their glomerular filtration rate as a result of fasting. 21 Another systemic review by Bragazzi looked into the effect of Ramadan fasting in 140 subjects with CKD including 40 on hemodialysis, 18 on peritoneal dialysis, and the rest not on dialysis yet. The author found no significant ill effects from fasting on these patients.…”

Section: Hemodialysis International 2015; ••:••-••mentioning

confidence: 99%

Changes in biochemical, hemodynamic, and dialysis adherence parameters in hemodialysis patients during Ramadan

Alshamsi

Binsaleh

Hejaili

et al. 2015

Hemodialysis International

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This paper aimed to study the effect of Ramadan fasting on biochemical and clinical parameters and compliance for dialysis. A prospective multicenter observational cross-sectional study comparing fasting with a non-fasting stable adult hemodialysis patients for demographic and biochemical parameters, compliance with dialysis, inter-dialytic weight gain, pre- and post-blood pressure, and frequency of intradialytic hypotensive episodes was carried out. Six hundred thirty-five patients, of whom 64.1% fasted, were studied. The fasters were younger (53.3 ± 16.2 vs. 58.4 ± 16.1 years; P = 0.001) but had similar duration on dialysis (P = 0.35). More fasters worked (22.0% vs. 14.6%; P = 0.001) and missed dialysis sessions during Ramadan. No differences were noted between groups in sex, diabetic status, or dialysis shift or day. There were no differences in the pre- and post-dialysis blood pressure; serum potassium, albumin or weight gain; diabetic status; sex; and dialysis shift time or days. However, serum phosphorous was significantly higher in the fasting group (2.78 ± 1.8 vs. 2.45 ± 1.6 mmol/L; P = 0.045). There were no intragroup differences in any of the parameters studied when comparing the findings during Ramadan with those in the month before Ramadan. Fasters were significantly younger and more likely to be working, to miss dialysis sessions, and to have higher serum phosphorous levels. No other differences were observed.

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“…This is especially true among those with chronic kidney disease (CKD), predisposing them to acute tubular injury. Additionally, dehydration is a major precipitating factor for renal stone development [40][41][42] . Antunes et al, 2017 stated that fasting increase the sensitivity of tumor cell lines to cisplatin-induced cells, and also of those cell lines particularly resistant to any pharmacological treatment [43] .…”

Section: Letter To the Editormentioning

confidence: 99%

Intermittent Fasting and Adding More days to Life

Mohiuddin

2019

Journal of Gastroenterology and Hepatology Research

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Intermittent fasting (IF) is currently one of the world's most popular health and fitness trends. Several IF patterns have been studied. Not all were shown to be equally effective. Also, each person's experience of intermittent fasting is individual, and different styles will suit different people. The potential health benefit list of IF is long: accelerated weight loss, reduced inflammation, lower cholesterol, longer lifespan, blood sugar stabilization, and prevention of type 2 diabetes. Emerging research suggests IF may also lead to a healthier brain, longer life, and even aid cancer treatment. Placing time restrictions on feeding has been shown to have broad systemic effects and trigger similar biological pathways as caloric restriction. One key mechanism responsible for many of these beneficial effects appears to be "flipping" of the metabolic switch. The metabolic switch typically occurs in the third phase of fasting when glycogen stores in hepatocytes are depleted and accelerated adipose tissue lipolysis produces increased fatty acids and glycerol. Just changing the timing of meals, by eating earlier in the day and extending the overnight fast, significantly benefited metabolism even in people who didn't lose a single pound.

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Ramadan fasting and chronic kidney disease: does estimated glomerular filtration rate change after and before Ramadan? Insights from a mini meta-analysis

Cited by 36 publications

References 15 publications

Does Ramadan Fasting Affect Hydration Status and Kidney Function in CKD Patients?

Does Ramadan Fasting Affect Hydration Status and Kidney Function in CKD Patients?

Changes in biochemical, hemodynamic, and dialysis adherence parameters in hemodialysis patients during Ramadan

Intermittent Fasting and Adding More days to Life

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