Radiological review of pleural tumors

Sureka, Binit; Thukral, Brij Bhushan; Mittal, Mahesh Kumar; Mittal, Aliza; Sinha, Mukul

doi:10.4103/0971-3026.125577

Cited by 41 publications

(32 citation statements)

References 15 publications

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“…[Tracheobronchial and alveolar pathway is reprinted from Comparative Biology of the Normal Lung, 2nd ed., Plopper CG and Hyde DM, Epithelial cells of the bronchiole, pp. 83–92, 2015, with permission from Elsevier; while thoracic and pleural region is adapted from Sureka et al (2013), with use permitted by the Indian Journal of Radiology] .…”

Section: Figurementioning

confidence: 99%

Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

Kuempel

Jaurand

Møller

et al. 2016

Critical Reviews in Toxicology

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In an evaluation of carbon nanotubes (CNTs) for the IARC Monograph 111, the Mechanisms Subgroup was tasked with assessing the strength of evidence on the potential carcinogenicity of CNTs in humans. The mechanistic evidence was considered to be not strong enough to alter the evaluations based on the animal data. In this paper, we provide an extended, in-depth examination of the in vivo and in vitro experimental studies according to current hypotheses on the carcinogenicity of inhaled particles and fibers. We cite additional studies of CNTs that were not available at the time of the IARC meeting in October 2014, and extend our evaluation to include carbon nanofibers (CNFs). Finally, we identify key data gaps and suggest research needs to reduce uncertainty. The focus of this review is on the cancer risk to workers exposed to airborne CNT or CNF during the production and use of these materials. The findings of this review, in general, affirm those of the original evaluation on the inadequate or limited evidence of carcinogenicity for most types of CNTs and CNFs at this time, and possible carcinogenicity of one type of CNT (MWCNT-7). The key evidence gaps to be filled by research include: investigation of possible associations between in vitro and early-stage in vivo events that may be predictive of lung cancer or mesothelioma, and systematic analysis of dose–response relationships across materials, including evaluation of the influence of physico-chemical properties and experimental factors on the observation of nonmalignant and malignant endpoints.

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Section: Figurementioning

confidence: 99%

Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

Kuempel

Jaurand

Møller

et al. 2016

Critical Reviews in Toxicology

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“…Correspondingly, Hamartomas were consistently found to be the most prevalent benign lung tumour in the west (12,13). Malignant pleural tumours are a less common entity (12). However, when both primary and secondary malignant tumours were taken together, they were commoner than benign pleural tumours ( 1 2 ) w h i c h w a s i n a c c o r d a n c e w i t h o u r s t u d y. Adenocarcinoma is the commonest histological type of the pleural secondaries worldwide (12).…”

Section: Discussionmentioning

confidence: 98%

“…Hamartoma was the most frequent benign lung tumour in our study accounting for 76% (n=13) of the benign neoplasms of the lung. Correspondingly, Hamartomas were consistently found to be the most prevalent benign lung tumour in the west (12,13). Malignant pleural tumours are a less common entity (12).…”

Section: Discussionmentioning

confidence: 99%

A descriptive analysis of lung and pleural tumours in a premier referral centre in Sri Lanka

et al. 2019

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IntroductionThis study describes pathological findings of lung and pleural neoplasms among a cohort of Sri Lankan patients. MethodsA descriptive cross-sectional study was conducted among patients with lung and pleural tumours referred to National Hospital for Respiratory Diseases in 2017. Patients who underwent biopsy under direct vision or radiological guidance were included. Contrast Enhanced Computerized Tomography (CECT) findings were correlated with the histological diagnosis. ResultsThe population was aged 8-93[mean (SD) =58.4(13.3)] years. Of 396 patients, 252(63.6%) were males. Majority (n=324, 81.4%) had lung tumours while 72(18.2%) had pleural tumours. Malignant neoplasms were found in 373(n=94.2). Of them, majority (n=180, 45.5%) were core biopsies, followed by lobectomies (n=77, 19.4%). Commonest benign lung tumour was hamartoma (n=13, 3.3%). Schwannoma was the commonest benign pleural tumour (n=3, 0.8%). Among the primary malignant lung tumours, adenocarcinoma was the commonest (n=124, 31.3%). Six (1.5%) primary malignant pleural neoplasms (mesotheliomas) were found. Among the metastatic deposits in the lung, the majority was colorectal adenocarcinomas (n=9, 2.3%). The sensitivity, specificity, positive and negative predictive values of CECT in discriminating malignant lung and pleural tumours were 94.6%, 90.9%, 99.3%, and 54.1% respectively. A one-way ANOVA showed significant differences in the distribution of age among different types of masses [F (5,396) =2.759, p=.018]. The age of patients with benign lung neoplasms (mean=51.3±17.4 years), was less compared to the malignant pleural tumours and primary malignant lung tumours.

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“…The pleural cavity presents the maximum optical density change at both 690 nm and 850 nm. As the pleural cavity is a cavity [33], it is expected that most of the light will directly penetrate through thin fluid-filled space, with only a few photons being absorbed, scattered, or reflected by the tissues of the pleural cavity. Therefore, the highest HbO 2 and Hb concentrations measured in the tissue of the pleural cavity may be inaccurate.…”

Section: Comparison To the Commercial Productsmentioning

confidence: 99%

A Novel Smart Assistance System for Blood Vessel Approaching: A Technical Report Based on Oximetry

Lee

Chuang

Lai

et al. 2020

Sensors

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In clinical practice, the catheter has to be placed at an accurate position during anesthesia administration. However, effectively guiding the catheter to the accurate position in deeper tissues can be difficult for an inexperienced practitioner. We aimed to address the current issues associated with catheter placement using a novel smart assistance system for blood vessel catheter placement. We used a hollow introducer needle embedded with dual wavelength (690 and 850 nm) optical fibers to advance the tip into the subclavian vessels in anesthetized piglets. The results showed average optical density changes, and the difference between the absorption spectra and hemoglobin concentrations of different tissue components effectively identified different tissues (p < 0.05). The radial basis function neural network (RBFNN) technique was applied to distinguish tissue components (the F-measure value and accuracy were 93.02% and 94%, respectively). Finally, animal experiments were designed to validate the performance of the proposed system. Using this system based on oximetry, we easily navigated the needle tip to the target vessel. Based on the experimental results, the proposed system could effectively distinguish different tissue layers of the animals.

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Radiological review of pleural tumors

Cited by 41 publications

References 15 publications

Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

A descriptive analysis of lung and pleural tumours in a premier referral centre in Sri Lanka

A Novel Smart Assistance System for Blood Vessel Approaching: A Technical Report Based on Oximetry

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