Radioimmunoassay of urinary antidiuretic hormone in man: Stimulation–suppression tests

Fressinaud, P; Corvol, P; Ménard, Joël; Allegrini, J

doi:10.1038/ki.1974.97

Cited by 29 publications

(14 citation statements)

References 23 publications

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“…Urinary values in adult subjects have gen erally been higher than those found in the present study [5,8,13,15]. This is unlikely to be due to loss of immunoreactive AVP before the urine was frozen, as recovery was similar between urine frozen immediately or left at room temperature for 24 h when it was acid ified in the ratio of 0.2 acid: 1 urine.…”

Section: Discussioncontrasting

confidence: 53%

“…We have demonstrated that urinary excre tion of AVP reflects plasma levels in infants as it does in adults [5,7,18]. The pattern of 24-hour urinary AVP excretion reflected changes seen in plasma AVP in that higher concentrations were seen in the first 2 days of life.…”

Section: Discussionmentioning

confidence: 90%

“…They were elevated after vaginal delivery and fell over the suc ceeding 48 h. However, the volume required for radioimmunoassay of AVP limits the use of determination in plasma in long-term studies in newborn infants. Bioassay [19] and radioimmunoassay [5,8] of urinary AVP have been developed and applied to studies in adult patients. We have developed a urine collection tray to facilitate long-term urine collection in infants and have used a ra dioimmunoassay for the determination of AVP in neonatal urine.…”

Section: Introductionmentioning

confidence: 99%

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Continuous Urine Collection in the Study of Vasopressin in the Newborn

1983

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We have evaluated the use of urinary vasopressin (AVP) measurements in human newborns to see if urinary AVP excretion is a true reflection of the plasma level. AVP was measured in 37 simultaneously collected plasma and urine samples. The correlation coefficient was 0.8 (p < 0.001). AVP extracted in duplicate from six urine samples was measured by bioassay and radioimmunoassay. The correlation coefficient was 0.85 (p < 0.05). To facilitate long-term urine collection we have developed a urine collecting tray to fit a standard incubator or cot. Urinary AVP was measured in 24-hour urine collections in 37 normal infants. AVP excretion was higher in the first 48 h of life than subsequently. Continuous 4-hour urine collections were made in 1 sick infant to assess AVP excretion when urine flow is variable.

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Section: Discussioncontrasting

confidence: 53%

Section: Discussionmentioning

confidence: 90%

Section: Introductionmentioning

confidence: 99%

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Continuous Urine Collection in the Study of Vasopressin in the Newborn

1983

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“…It seemed to be due to differences in hydration and the activity of other physiological processes of each subject which could affect AVP secretion apart from plasma osmolality (Dunn et al 1973;Kimura et al 1976 Daily urinary excretion of AVP in the normal and the various patients were almost equivalent to the values reported previously by several authors (Miller and Moses 1972;Fressinaud et al 1974;Merkelbach et al 1975). In patients with diabetes insipidus, urinary AVP could be detectable, although extremely low (about 14% of normal values), indicating that most of these patients have a residual function in the neurohypophysis to secrete a small amount of AVP into the blood despite of marked polyuria.…”

Section: Discussionsupporting

confidence: 71%

“…Resin column chromatography has been used frequently for the radioimmunoas say of urinary AVP (Miller and Moses 1972;Fressinaud et al 1974;Merkelbach et al 1975), but scarcely for the radioimmunoassay of plasma AVP except the measurement of dog plasma AVP by Shade and Share (1975). It has never been applied for the radioimmunoassay of human plasma AVP.…”

Section: Discussionmentioning

confidence: 99%

Radioimmunoassay of arginine vasopressin in human plasma and urine, a resin microcolumn method.

Kimura

Matsui

Ota

et al. 1980

Tohoku J. Exp. Med.

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Antihypertensive and hormonal effects of single oral doses of Captopril and Nifedipine in essential hypertension

Soto

Thibonnier

Sire

et al. 1981

Eur J Clin Pharmacol

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In a single-dose crossover study Captopril (SQ 14225), 1 mg/kg body weight, and Nifedipine (Bay a 1040) 20 mg were administered orally to 12 hospitalized patients with essential hypertension (Stage 1 or 2, W.H.O.). Both drugs significantly reduced blood pressure, but each dose acted differently: the mean maximum arterial pressure reduction was faster and greater with Nifedipine than with Captopril: -23 +/- 2% at 37 +/- 15 min and -17 +/- 1% at 86 +/- 25 min, respectively. Captopril inhibited angiotensin II and aldosterone production, but did not accelerate heart rate or stimulate vasopressin release. Nifedipine stimulated vasopressin release and increased heart rate, but the renin angiotensin aldosterone system was not significantly affected. The blood pressure reduction was related to the initial level of activation of the renin angiotensin system only for Captopril. The blood pressure reduction induced by one drug was not related to that produced by the other in the same patient.

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Radioimmunoassay of urinary antidiuretic hormone in man: Stimulation–suppression tests

Cited by 29 publications

References 23 publications

Continuous Urine Collection in the Study of Vasopressin in the Newborn

Continuous Urine Collection in the Study of Vasopressin in the Newborn

Radioimmunoassay of arginine vasopressin in human plasma and urine, a resin microcolumn method.

Antihypertensive and hormonal effects of single oral doses of Captopril and Nifedipine in essential hypertension

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