Radiographic Features of Central Nervous System Vasculitis

Wynne, Peter J.; Younger, David S.; Khandji, Alexander G.; Silver, A J

doi:10.1016/s0733-8619(05)70347-9

Cited by 24 publications

(21 citation statements)

References 104 publications

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“…[96] Vasculitides are often distinguished from other RPDs by brain MRI abnormalities, such as strokes and/or hemorrhage involving both the white or gray matter. [96] Similarly, body imaging for systemic involvement may be helpful [97] When primary CNS vasculitis is suspected, cerebral angiogram or brain and meningeal brain biopsy of the affected area may be required for diagnosis. Intravascular lymphoma sometimes mimics CNS vasculitis on angiogram; if this condition is suspected (based on an elevated serum LDH or MRI findings), then doctors should avoid the angiogram and go directly to biopsy.…”

Section: Vascularmentioning

confidence: 99%

Rapidly Progressive Dementia

2007

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Rapidly progressive dementias (RPDs) are neurological conditions that develop subacutely over weeks to months, or rarely acutely over days. In contrast to most dementing conditions that take years to progress to death, RPD can be quickly fatal. It is critical to evaluate the RPD patient without delay, usually in a hospital setting, as they may have a treatable condition. In this review, we discuss a differential diagnostic approach to RPD, emphasizing neurodegenerative, toxic/metabolic, infectious, autoimmune, neoplastic, and other conditions to consider.

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Section: Vascularmentioning

confidence: 99%

Rapidly Progressive Dementia

2007

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“…Index terms: CNS vasculitis; magnetic resonance imaging; perfusion imaging; diffusion imaging; cerebral angiography DIAGNOSIS of central nervous system (CNS) vasculitis has always been a challenge (1,2). It is an inflammatory vascular disease that can be caused by many etiologies (3,4).…”

mentioning

confidence: 99%

“…It is an inflammatory vascular disease that can be caused by many etiologies (3,4). CNS vasculitis usually involves the small blood vessels of the parenchyma and meninges, which may not be effectively evaluated by traditional radiological means (1)(2)(3)(4)(5). Although it is a very rare disease entity, clinical suspicion of CNS vasculitis is an almost daily event.…”

mentioning

confidence: 99%

Diagnosis of microvasculopathy in CNS vasculitis: Value of perfusion and diffusion imaging

Yuh

Ueda

Maley

et al. 1999

J. Magn. Reson. Imaging

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“…The angiographic signs include multifocal, segmental stenosis with smooth or slightly irregular contours, dilatation, occlusions, collateral formation, prolonged circulation time, beading, and aneurysmal formation [28][29][30] (Fig. 3).…”

Section: Vasculopathymentioning

confidence: 99%

“…3). In polyarteritis nodosa, the coexistence of visceral (hepatic, renal, mesenteric, celiac) microaneurysms, present in 75% of cases, may be extremely helpful for the diagnosis of this disease [28][29][30]. MRA alone may be sufficient to make the diagnosis of vasculitis if more than two stenoses in at least two separate vascular distributions are found [15].…”

Section: Vasculopathymentioning

confidence: 99%

Ischemic stroke: carotid and vertebral artery disease

Vilela

Goulão

2005

Eur Radiol

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Ischemic strokes may have distinct aetiologies, including several different intrinsic arterial pathological disorders. The diagnosis and understanding of these arterial diseases is critical for the correct management of stroke as different treatment approaches are undertaken according to the aetiology. Atherosclerosis is by far the most common arterial disease among adults, and other pathological processes include arterial dissection, small vessel disease, inflammatory and non-inflammatory vasculopathy and vasomotor disorders. In children, there are several vasculopathies responsible for vaso-occlusive disease such as sickle-cell anemia, acute regressive angiopathy and Moya-Moya disease, neurofibromatosis, dissections, vasculitis associated with intracranial and systemic infections. An overview of the major carotid and vertebral pathological diseases responsible for ischemic stroke in adults and children, highlighting the accuracy of the different imaging modalities for its diagnosis and the imaging appearance of these diseases, is given.

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Radiographic Features of Central Nervous System Vasculitis

Cited by 24 publications

References 104 publications

Rapidly Progressive Dementia

Rapidly Progressive Dementia

Diagnosis of microvasculopathy in CNS vasculitis: Value of perfusion and diffusion imaging

Ischemic stroke: carotid and vertebral artery disease

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